Amine Ouaket, Boutaina Addoum, B. E. Khalfi, A. Soukri, N. Knouzi, M. Berrada
{"title":"某些双苯并咪唑对嗜热四膜虫应激细胞抗氧化活性的研究","authors":"Amine Ouaket, Boutaina Addoum, B. E. Khalfi, A. Soukri, N. Knouzi, M. Berrada","doi":"10.48317/IMIST.PRSM/MORJCHEM-V9I2.20868","DOIUrl":null,"url":null,"abstract":"In this paper, we present experimental findings on the protective effect of some bis-benzimidazole molecules against oxidative (H 2 O 2 ) and nitrosative (SNP) stress using the protozoan T. thermophila as a cellular model. The results of this article show that the molecules 2,2’-Benzendiyl-1,4-Bis-(5-amino-1H-benzimidazole) and 2,2’-Octandiyl-1,8-Bis-(quinolin-8-ol-5-azo-1H-benzimidazole) have a protective effect against stress important than the molecule 2,2’-Benzendiyl-1,4-Bis-(1H-benzimidazole).","PeriodicalId":18768,"journal":{"name":"Moroccan Journal of Chemistry","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2021-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Investigation of antioxidant activity of some bis-benzimidazole in Tetrahymena thermophila stressed cells\",\"authors\":\"Amine Ouaket, Boutaina Addoum, B. E. Khalfi, A. Soukri, N. Knouzi, M. Berrada\",\"doi\":\"10.48317/IMIST.PRSM/MORJCHEM-V9I2.20868\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this paper, we present experimental findings on the protective effect of some bis-benzimidazole molecules against oxidative (H 2 O 2 ) and nitrosative (SNP) stress using the protozoan T. thermophila as a cellular model. The results of this article show that the molecules 2,2’-Benzendiyl-1,4-Bis-(5-amino-1H-benzimidazole) and 2,2’-Octandiyl-1,8-Bis-(quinolin-8-ol-5-azo-1H-benzimidazole) have a protective effect against stress important than the molecule 2,2’-Benzendiyl-1,4-Bis-(1H-benzimidazole).\",\"PeriodicalId\":18768,\"journal\":{\"name\":\"Moroccan Journal of Chemistry\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2021-02-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Moroccan Journal of Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.48317/IMIST.PRSM/MORJCHEM-V9I2.20868\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Moroccan Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.48317/IMIST.PRSM/MORJCHEM-V9I2.20868","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Investigation of antioxidant activity of some bis-benzimidazole in Tetrahymena thermophila stressed cells
In this paper, we present experimental findings on the protective effect of some bis-benzimidazole molecules against oxidative (H 2 O 2 ) and nitrosative (SNP) stress using the protozoan T. thermophila as a cellular model. The results of this article show that the molecules 2,2’-Benzendiyl-1,4-Bis-(5-amino-1H-benzimidazole) and 2,2’-Octandiyl-1,8-Bis-(quinolin-8-ol-5-azo-1H-benzimidazole) have a protective effect against stress important than the molecule 2,2’-Benzendiyl-1,4-Bis-(1H-benzimidazole).
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