从海洋真菌木霉QD-11中提取的一种新的胡萝卜素倍半萜

IF 1.5 4区 生物学 Q3 CHEMISTRY, APPLIED Records of Natural Products Pub Date : 2022-08-14 DOI:10.25135/rnp.349.2206.2492
Lin-chuan Jia, Xiao-Xiao Liu, Wen-Ting Yang, Wei-ping Gao, Jin-An Liu
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引用次数: 1

摘要

:从海生真菌绿色木霉QD-11的培养基中分离到一种新的角蛋白倍半萜,即三角蛋白N(1)。通过1D/2D NMR和HRESIMS数据的详细分析确定了该化合物的结构。Trichocarotin N(1)对HeLa和MCF-7癌症细胞系表现出中等的细胞毒性,IC50值分别为32.4和41.6μM。出版物。保留所有权利。
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TTrichocarotin N: a New Carotane Sesquiterpene from the Marine-Derived Fungus Trichoderma virens QD-11
: A new carotane sesquiterpene, trichocarotin N ( 1 ), was isolated from a culture of the marine-derived fungus Trichoderma virens QD-11. The structure of this compound was established by detailed analysis of 1D/2D NMR and HRESIMS data. Trichocarotin N ( 1 ) exhibited moderate cytotoxicity against HeLa and MCF-7 cancer cell lines, with IC 50 values of 32.4 and 41.6 μM, respectively. Publications. All rights reserved.
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来源期刊
Records of Natural Products
Records of Natural Products 生物-医药化学
CiteScore
3.10
自引率
26.30%
发文量
78
审稿时长
4 months
期刊介绍: Records of Natural Products is a journal of natural product chemistry. Reviews, book reviews, research papers and short reports are considered on the substances of plants, microbes and animals. Discussions on the structure elucidation, synthesis of naturally occurring compounds and biological activity of natural compounds and plant extracts, biosynthesis of natural products and essential oils of aromatic plants as well as chemotaxonomy in the field of plants are welcomed in the journal. All published research articles in Records of Natural Products have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by expert referees.
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