纳米技术修饰驱虫药(综述)

Rossiiskii parazitologicheskii zhurnal Pub Date : 2022-06-14 DOI:10.31016/1998-8435-2022-16-2-213-229

A. I. Varlamova, I. Arkhipov, S. Khalikov, M. Arisov

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引用次数: 0

摘要

本研究的目的是分析和总结文献资料和我们自己的研究结果，利用药物传递系统和方法来提高驱虫药的溶解度和有效性。寄生虫病是兽医学和畜牧业中最重要的问题之一，不仅由于其病理作用，而且由于寄生虫耐药性的传播。由于开发新的驱虫药需要多年的时间和投资，目前的一些策略侧重于对现有药物进行修饰，以提高其疗效，减少副作用和克服驱虫药耐药性。对提高驱虫药溶解度和药效的各种方法和手段进行了文献资料分析，并对其应用前景进行了展望，包括利用现代纳米技术给药的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Modifcation of anthelmintic drugs by nanotechnology (review)

The purpose of the research is to analyze and summarize the literature data and the results of our own studies on the use of drug delivery systems and methods for increasing the solubility and efcacy of anthelmintic drugs.Helminthoses are one of the most important problems in veterinary medicine and animal husbandry, not only due to the pathological eﬀects, but also due to the spread of anthelmintic resistance. Since the development of new anthelmintic substances takes many years and investment, some strategies are currently focused on modifying existing drugs to increase their efcacy, reduce side eﬀects and overcome anthelmintic resistance. Literature data analysis on various methods and means of increasing the solubility and efcacy of anthelmintic drugs was carried out and the prospects for their use, including using modern nanotechnological methods of drug delivery were given.

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Rossiiskii parazitologicheskii zhurnal

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8 weeks