COVID-19细胞治疗综述及潜在应用

D. Câmara, A. Porcacchia, N. Lizier, P. L. de-Sá-Júnior
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引用次数: 2

摘要

新冠肺炎大流行已经夺走了数千人的生命,尽管许多科学研究已经表明了这种情况的可能性。目前,人们进一步关注患有呼吸道或免疫功能低下疾病、高血压和糖尿病等合并症的患者,因为这些患者的预后较差。使用干细胞和/或防御细胞的细胞疗法,无论是否与传统治疗相结合,都可能是新冠肺炎治疗的杰出策略,因为这些治疗可以通过调节免疫系统、减少增殖和有利于完全消除病毒来发挥作用。在这篇综述中,我们强调了这种新型冠状病毒的主要分子特征,以及新冠肺炎的主要病理特征。此外,还指出了可能的细胞疗法,以显示针对新冠肺炎及其后续疾病的替代疗法。
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A COVID-19 Overview and Potential Applications of Cell Therapy
The COVID-19 pandemic has already reaped thousands of lives, although many scientific studies already showed the possibility of this scenario. Currently, further attention is provided to patients depicting comorbidities such as respiratory or immunocompromised diseases, hypertension, and diabetes, as these individuals show a worse prognosis. Cell therapies using stem cells and/or defense cells, combined or not with traditional treatment, could be an outstanding strategy for COVID-19 management since these treatments can act by modulating the immune system, reducing proliferation, and favoring the complete elimination of the virus. In this review, we highlight the main molecular characteristics of this novel coronavirus, as well as the main pathognomonic signs of COVID-19. Furthermore, possible cell therapies are pointed out to show alternative treatments against COVID-19 and its sequels.
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