{"title":"原发性骨髓纤维化预后评分系统的研究现状","authors":"Junying Wu","doi":"10.3760/CMA.J.ISSN.1673-419X.2019.04.001","DOIUrl":null,"url":null,"abstract":"The clinical presentation and prognosis for patients with primary myelofibrosis (PMF) are of highly heterogeneous. Several risk stratification models are raised in order to stratify patients accurately and guide appropriate treatment decisions. Recently, the cytogenetic and molecular pathogenesis of patients with PMF have been elucidated considerably. Therefore, prognostic scoring systems are updating to improve prognostic effectiveness and guidance value for therapy decisions. This article summarizes the advances of prognostic factors, the advantages and disadvantages of different prognostic scoring systems and the practical usefulness of the prognostic scoring systems in terms of clinical decision making. \n \n \nKey words: \nPrimary myelofibrosis; Myeloproliferative disorders; Myelofibrosis; Prognostic factors; Prognostic scoring systems; Genetics","PeriodicalId":13774,"journal":{"name":"国际输血及血液学杂志","volume":"42 1","pages":"277-282"},"PeriodicalIF":0.0000,"publicationDate":"2019-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Current research status of prognostic scoring systems in primary myelofibrosis\",\"authors\":\"Junying Wu\",\"doi\":\"10.3760/CMA.J.ISSN.1673-419X.2019.04.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The clinical presentation and prognosis for patients with primary myelofibrosis (PMF) are of highly heterogeneous. Several risk stratification models are raised in order to stratify patients accurately and guide appropriate treatment decisions. Recently, the cytogenetic and molecular pathogenesis of patients with PMF have been elucidated considerably. Therefore, prognostic scoring systems are updating to improve prognostic effectiveness and guidance value for therapy decisions. This article summarizes the advances of prognostic factors, the advantages and disadvantages of different prognostic scoring systems and the practical usefulness of the prognostic scoring systems in terms of clinical decision making. \\n \\n \\nKey words: \\nPrimary myelofibrosis; Myeloproliferative disorders; Myelofibrosis; Prognostic factors; Prognostic scoring systems; Genetics\",\"PeriodicalId\":13774,\"journal\":{\"name\":\"国际输血及血液学杂志\",\"volume\":\"42 1\",\"pages\":\"277-282\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-07-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"国际输血及血液学杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1673-419X.2019.04.001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"国际输血及血液学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-419X.2019.04.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Current research status of prognostic scoring systems in primary myelofibrosis
The clinical presentation and prognosis for patients with primary myelofibrosis (PMF) are of highly heterogeneous. Several risk stratification models are raised in order to stratify patients accurately and guide appropriate treatment decisions. Recently, the cytogenetic and molecular pathogenesis of patients with PMF have been elucidated considerably. Therefore, prognostic scoring systems are updating to improve prognostic effectiveness and guidance value for therapy decisions. This article summarizes the advances of prognostic factors, the advantages and disadvantages of different prognostic scoring systems and the practical usefulness of the prognostic scoring systems in terms of clinical decision making.
Key words:
Primary myelofibrosis; Myeloproliferative disorders; Myelofibrosis; Prognostic factors; Prognostic scoring systems; Genetics
期刊介绍：
The International Journal of Transfusion and Hematology was founded in September 1978. It is a comprehensive academic journal in the field of transfusion and hematology, supervised by the National Health Commission and co-sponsored by the Chinese Medical Association, West China Second Hospital of Sichuan University, and the Institute of Transfusion Medicine of the Chinese Academy of Medical Sciences. The journal is a comprehensive academic journal that combines the basic and clinical aspects of transfusion and hematology and is publicly distributed at home and abroad. The International Journal of Transfusion and Hematology mainly reports on the basic and clinical scientific research results and progress in the field of transfusion and hematology, new experiences, new methods, and new technologies in clinical diagnosis and treatment, introduces domestic and foreign research trends, conducts academic exchanges, and promotes the development of basic and clinical research in the field of transfusion and hematology.
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