胰岛素对妊娠期皮马印第安传统女性的影响

R. Das, Ishita Saha, Debjit Konai, S. K. Medda
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引用次数: 0

摘要

糖尿病和肥胖症在世界各地已达到流行病的程度,而胰岛素抵抗的影响及其后果也日益突出。本文推导了胰岛素对21岁以上皮马印第安血统女性妊娠期的影响。本文发现,妊娠妇女平均胰岛素水平(GW)与血糖水平呈正相关(P=0.0055),与年龄呈负相关(P=0.0095)。GW患者的平均胰岛素水平与妊娠期(P=0.1866)和糖尿病谱系功能(DPF)无关(P=0.5321),与妊娠期*DPF的共同作用部分正相关(P=0.0864)。与血压(BP) (P<0.0001)、三头肌皮褶厚度(TST) (P<0.0001)呈正相关,与BP*TST (P<0.0001)、DPF*TST (P<0.0001)联合作用呈负相关。平均胰岛素水平与体重指数(BMI)呈负相关(P=0.0001),与BMI*DPF交互效应呈部分正相关(P=0.1312)。胰岛素水平方差与妊娠期(P=0.0184)、年龄(P=0.0027)呈正相关,与妊娠期*年龄(P=0.0418)负相关。胰岛素水平的方差与BMI (P=0.0738)和葡萄糖水平(P=0.1439)呈部分负相关,与BMI*葡萄糖的共同作用呈部分正相关(P=0.1472)。胰岛素水平的方差与DPF呈负相关(P=0.0309)。综上所述,GW患者胰岛素水平随血糖水平、BP、TST的升高而升高,并与妊娠期*DPF和BMI*DPF相互作用,胰岛素水平随年龄、BMI的升高而降低,与BP*TST和DPF*TST相互作用。GW应该注意她的血糖水平、BMI、血压和TST。
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Effects of Insulin on Gestational Pima Indian Heritage Females
Diabetes and obesity reach epidemic proportions all over the world, while the effects of insulin resistance and its consequences are gaining prominence. The article derives the effects of insulin on gestational Pima Indian heritage females with minimum 21 years old. It is identified herein that mean insulin level for gestational women (GW) is positively linked with glucose level (P=0.0055), while it is negatively linked with age (P=0.0095). Mean insulin level for GW is independent of pregnancies (P=0.1866) and diabetes pedigree function (DPF) (P=0.5321), while it is partially positively linked with their joint interaction effect Pregnancies*DPF (P=0.0864). It is positively linked with blood pressure (BP) (P<0.0001) and triceps skin-fold thickness (TST) (P<0.0001), while it is negatively linked with the joint interaction effects BP*TST (P<0.0001) and DPF*TST (P<0.0001). In addition, mean insulin level is negatively linked with body mass index (BMI) (P=0.0001), while it is positively partially linked with the interaction effect BMI*DPF (P=0.1312). Variance of insulin level is positively linked with pregnancies (P=0.0184) and age (P=0.0027), while it is negatively linked with their joint interaction effect Pregnancies*Age (P=0.0418). Also variance of insulin level is partially negatively linked with BMI (P=0.0738) and glucose level (P=0.1439), while it is partially positively linked with their joint interaction effect BMI*Glucose (P=0.1472). Further, variance of insulin level is negatively linked with DPF (P=0.0309). It is concluded that for GW, insulin level increases with the increase of glucose level, BP, TST, and the interaction effects Pregnancies*DPF & BMI*DPF, and it decreases with the increase age, BMI, and the interaction effects BP*TST & DPF*TST. GW should be careful on her glucose level, BMI, BP & TST.
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