Comparative evaluation of N-acetylcysteine and chlorhexidine as final irrigation on the push-out bond strength of different sealers: An in vitro study

Aim: Using N acetyl cysteine (NAC) and Chlorhexidine as final irrigants, the study aims to examine the push out bond strength of distinct sealers. Materials and Methods: Access and biomechanical preparation were done on decoronated 80 single-rooted teeth. Canals were alternatively irrigated using 5ml of 5.25% NaOCl and 5ml of 17% EDTA solution during instrumentation. On the basis of final irrigation procedure, the samples are divided into two groups: Group 1 – NAC and Group 2 – 2% Chlorhexidine. Using paper points, canals were dried and subdivided depending on the sealers used, Group 1A and 2A- AH plus and 1B and 2B- BioRoot RCS. Teeth were obturated and middle root sections were tested for push-out bond strength using universal testing equipment. Statistical analysis was done. Results: NAC with AH-plus sealer had the maximum push-out strength, whereas Chlorhexidine with BioRoot RCS sealer had the lowest. Conclusion: NAC increases the bond strength of the obturating materials as the final irrigant. NAC can be considered as a final irrigant for endodontic therapy.