舌癌症机械损伤病因的早期诊断

Aris Setyawan, Zhavira Dwiyanti Anang, Rizki Nurida Rahmawati, Winda Kumalasari, Alfi Dian Uly Noor, R. Yulianti
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引用次数: 1

摘要

背景:口腔鳞状细胞癌(OSCC)发生在大约95%的40岁以上的人群中;通常在60岁时被诊断出来。OSCC的病因是多因素的。由于锋利的牙齿引起的慢性机械创伤也被认为是口腔鳞状舌头的病因。目的:本病例报告旨在描述机械性损伤引起的OSCC的病因,并通过早期正确诊断病变防止进一步转移。病例:一名49岁女性患者,两个月前出现疼痛和肿胀的口腔炎。未见下颌下淋巴结。口腔内检查发现右颌有硬化溃疡及尖牙。组织病理学检查(HPE)和磁共振成像(MRI)结果均判定为恶性。病例处理:选择多次拔除,以消除因锋利牙齿造成机械损伤的病因,患者采用锁眼法行半盲切除术。术后,组织病理学检查显示舌鳞癌。该患者目前正处于血液肿瘤学家化疗的第二周期。结论:早期正确诊断舌溃疡可预防转移,降低发病率,提高生活质量。
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The early detection of tongue cancer with the etiology of mechanical trauma
Background: Oral squamous cell carcinoma (OSCC) occurs in approximately 95% of people older than 40 years; usually, it is diagnosed at the age of 60 years. The etiology of OSCC is multifactorial. Chronic mechanical trauma due to sharp teeth has also been suggested as an etiology of oral squamous of the tongue. Purpose: This case report aimed to describe the etiology of OSCC resulting from mechanical trauma and to prevent further metastasis by correctly diagnosing the lesion earlier. Case: A 49-year-old female patient presented with painful and swollen stomatitis two months ago. No submandibular lymph nodes were palpable. An indurated ulceration and sharp teeth on the right region of the jaw were obtained from the intraoral examination. Malignancy was concluded from Histopathology Examination (HPE) and Magnetic Resonance Imaging (MRI) radiography results. Case Management: Multiple extractions were chosen to eliminate the etiology of mechanical trauma due to sharp teeth, and the patient underwent hemiglossectomy with the keyhole method. Postoperative, the histopathology examination revealed an OSCC of the tongue. The patient is currently in the second cycle of chemotherapy by hematologist-oncologists. Conclusion: The early appropriate diagnosis of a tongue ulcer can prevent metastasis, decrease morbidity, and increase quality of life.
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