尼日利亚卡诺地区成釉细胞瘤组织病理模式的审计

A. Sule, TE IyogunAdeyemi, C. Iyogun
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摘要

目的:描述卡诺州成釉细胞瘤的频谱、频率、年龄和性别分布,并与尼日利亚、非洲和世界其他地区的研究结果进行比较。材料和方法:这是一项为期5年的回顾性研究,从2010年1月2日至2014年12月31日,在尼日利亚卡诺的Aminu Kano教学医院病理部门诊断的所有成膜细胞瘤。结果:在5年的研究期间确诊成釉细胞瘤64例,男女比例为2:1。年龄16 ~ 75岁(平均33.4岁),40 ~ 49岁为发病的相对高峰年龄。实性/多囊型占多数(57例,89.1%),其次为单囊型(5例,7.8%),其余2例为结缔组织增生型和外周型(3.1%)。下颌骨是最常见的受累部位,57例(89.1%),上颌和牙槽黏膜分别占6例(9.4%)和1例(1.6%)。结论:本研究显示成釉细胞瘤有明显的男性偏好,主要影响年龄在30岁至50岁之间的患者。结果显示,实体/多囊性成釉细胞瘤的发病率高于单囊性变异体。人口统计学和组织学特征与尼日利亚其他地区和其他地方的报告相似。
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An Audit of the Histopathological Pattern of Ameloblastoma in Kano, Nigeria
Objective: To describe the spectrum, frequency, age and sex distribution of ameloblastomas seen in Kano, as well as compare the findings with  previous studies done in Nigeria, Africa and other parts of the world. Materials and Methods: This was a 5 year retrospective study from 2nd January, 2010 to 31st December, 2014 of all ameloblastomas diagnosed at the pathology department of Aminu Kano Teaching Hospital, Kano, Nigeria. Results: Sixty four cases of ameloblastomas were diagnosed during the five year study period with a male to female ratio of 2:1. The ages ranged from 16 to 75 years (mean age of 33.4) and relative peak age of incidence occurred in the 40 - 49 years group. Solid/Multicystic type accounted for majority (57 cases, 89.1%) of ameloblastomas followed by unicystic variant (5 cases,7.8%), while the desmoplastic and peripheral variants  comprising the remaining 2 cases (3.1%). The mandible was the commonest site of involvement accounting for 57cases(89.1%), while maxilla and alveolar mucosa accounted for 6 cases (9.4%) and 1case (1.6%) respectively. Conclusion: This study showed that ameloblastoma has significant male predilection and affecting predominantly patients in the third to fifth  decades. It revealed a higher incidence of solid/multicystic ameloblastomas over unicystic variants. The demographic and histological features are similar to reports from other parts of Nigeria and elsewhere.  
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