Michael B. La Monica, D. Fukuda, Ran Wang, Adam M. Gonzalez, Adam J. Wells, J. Hoffman, Jeffrey R Stout
{"title":"缓释咖啡因维持迷走神经张力，但在咖啡因习惯的男性安慰剂期间迷走神经戒断","authors":"Michael B. La Monica, D. Fukuda, Ran Wang, Adam M. Gonzalez, Adam J. Wells, J. Hoffman, Jeffrey R Stout","doi":"10.1089/CAFF.2017.0039","DOIUrl":null,"url":null,"abstract":"Objective: This study aimed to determine the effects of a time-release caffeine (TR-CAF) supplement and caffeine abstinence on heart rate variability (HRV) in habitual users. Methods: Ten caffeine-habituated (>200 mg per day) men (25.9 ± 3.2 years; 1.81 ± 0.08 m; and 92.9 ± 9.9 kg) performed three trials, each separated by 1 week. During each trial, participants randomly consumed either 194 mg of caffeine in a multi-ingredient supplement containing TR-CAF; an instant-release caffeine supplement (CAF); or placebo (PL). HRV was assessed for 10 minutes in the supine position at baseline (BL), and every hour after supplementation for 8 hours. Time-domain [average heart rate, mean standard deviation of all normal-to-normal (NN) intervals (SDNN), and root mean square of differences between adjacent NN intervals (RMSSD)] and frequency-domain [low frequency (LF), high frequency (HF), total power (TP), LF/HF, and an index of parasympathetic nervous system (PNS = HF/TP)] measures were recorded. A two-way (trial × t...","PeriodicalId":15112,"journal":{"name":"Journal of Caffeine and Adenosine Research","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/CAFF.2017.0039","citationCount":"3","resultStr":"{\"title\":\"Maintenance of Vagal Tone with Time-Release Caffeine, But Vagal Withdrawal During Placebo in Caffeine-Habituated Men\",\"authors\":\"Michael B. La Monica, D. Fukuda, Ran Wang, Adam M. Gonzalez, Adam J. Wells, J. Hoffman, Jeffrey R Stout\",\"doi\":\"10.1089/CAFF.2017.0039\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: This study aimed to determine the effects of a time-release caffeine (TR-CAF) supplement and caffeine abstinence on heart rate variability (HRV) in habitual users. Methods: Ten caffeine-habituated (>200 mg per day) men (25.9 ± 3.2 years; 1.81 ± 0.08 m; and 92.9 ± 9.9 kg) performed three trials, each separated by 1 week. During each trial, participants randomly consumed either 194 mg of caffeine in a multi-ingredient supplement containing TR-CAF; an instant-release caffeine supplement (CAF); or placebo (PL). HRV was assessed for 10 minutes in the supine position at baseline (BL), and every hour after supplementation for 8 hours. Time-domain [average heart rate, mean standard deviation of all normal-to-normal (NN) intervals (SDNN), and root mean square of differences between adjacent NN intervals (RMSSD)] and frequency-domain [low frequency (LF), high frequency (HF), total power (TP), LF/HF, and an index of parasympathetic nervous system (PNS = HF/TP)] measures were recorded. A two-way (trial × t...\",\"PeriodicalId\":15112,\"journal\":{\"name\":\"Journal of Caffeine and Adenosine Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2018-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1089/CAFF.2017.0039\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Caffeine and Adenosine Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1089/CAFF.2017.0039\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Caffeine and Adenosine Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/CAFF.2017.0039","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Maintenance of Vagal Tone with Time-Release Caffeine, But Vagal Withdrawal During Placebo in Caffeine-Habituated Men
Objective: This study aimed to determine the effects of a time-release caffeine (TR-CAF) supplement and caffeine abstinence on heart rate variability (HRV) in habitual users. Methods: Ten caffeine-habituated (>200 mg per day) men (25.9 ± 3.2 years; 1.81 ± 0.08 m; and 92.9 ± 9.9 kg) performed three trials, each separated by 1 week. During each trial, participants randomly consumed either 194 mg of caffeine in a multi-ingredient supplement containing TR-CAF; an instant-release caffeine supplement (CAF); or placebo (PL). HRV was assessed for 10 minutes in the supine position at baseline (BL), and every hour after supplementation for 8 hours. Time-domain [average heart rate, mean standard deviation of all normal-to-normal (NN) intervals (SDNN), and root mean square of differences between adjacent NN intervals (RMSSD)] and frequency-domain [low frequency (LF), high frequency (HF), total power (TP), LF/HF, and an index of parasympathetic nervous system (PNS = HF/TP)] measures were recorded. A two-way (trial × t...
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