{"title":"5-氯和5-叠氮-1,3-二苯基- 1h -吡唑-4-乙醛衍生物的合成","authors":"M. Farhat","doi":"10.47014/15.1.4","DOIUrl":null,"url":null,"abstract":"N-[(5-Azido-1,3-diphenyl-1H-pyrazole-4-yl)methylene]-N-arylamines (4a-c) and N-[(5-Substituted-1,3-diphenyl-1H-pyrazole-4-yl)methylene]hydrazides (5a-e) were prepared from 5-azido-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (3) and 5-chloro-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (2), respectively. Thermolysis of (4a-c) and (5d-e) afforded 5-arylamino-1,3-diphenyl-1H-pyrazol-4-carbonitriles (8a-c) and N-(4-cyano-1,3-diphenyl-1H-pyrazol-5-yl)hydrazides (13a,b), respectively. N-[2-(5-Chloro-1,3-diphenyl-1H-pyrazol-4-yl)-4-oxo-thiazolidin-3-yl]amides (14a,b) and 3-acetyl-2-(5-chloro-1,3-diphenyl-1H-pyrazol-4-yl)-5-aryl-2,3-dihydro-1,3,4-oxadiazoles (15a,b) were obtained from N-[(5-chloro-1,3-diphenyl-1H-pyrazole-4-yl)methylene]hydrazides (5a,b). 5-Azido-1,3-diphenyl-1H-pyrazol-4-carbaldehyde (3) gave unexpectedly 1-(1,3-diphenyl-1,6-dihydropyrrolo-2,3-c]pyrazol-5-yl)ethan-1-one (17).","PeriodicalId":14654,"journal":{"name":"Jordan Journal of Chemistry","volume":" ","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2020-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis of Some Pyrazole Derivatives from 5-Chloro- and 5-Azido-1,3-diphenyl-1H-pyrazole-4-carbaldehydes\",\"authors\":\"M. Farhat\",\"doi\":\"10.47014/15.1.4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"N-[(5-Azido-1,3-diphenyl-1H-pyrazole-4-yl)methylene]-N-arylamines (4a-c) and N-[(5-Substituted-1,3-diphenyl-1H-pyrazole-4-yl)methylene]hydrazides (5a-e) were prepared from 5-azido-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (3) and 5-chloro-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (2), respectively. Thermolysis of (4a-c) and (5d-e) afforded 5-arylamino-1,3-diphenyl-1H-pyrazol-4-carbonitriles (8a-c) and N-(4-cyano-1,3-diphenyl-1H-pyrazol-5-yl)hydrazides (13a,b), respectively. N-[2-(5-Chloro-1,3-diphenyl-1H-pyrazol-4-yl)-4-oxo-thiazolidin-3-yl]amides (14a,b) and 3-acetyl-2-(5-chloro-1,3-diphenyl-1H-pyrazol-4-yl)-5-aryl-2,3-dihydro-1,3,4-oxadiazoles (15a,b) were obtained from N-[(5-chloro-1,3-diphenyl-1H-pyrazole-4-yl)methylene]hydrazides (5a,b). 5-Azido-1,3-diphenyl-1H-pyrazol-4-carbaldehyde (3) gave unexpectedly 1-(1,3-diphenyl-1,6-dihydropyrrolo-2,3-c]pyrazol-5-yl)ethan-1-one (17).\",\"PeriodicalId\":14654,\"journal\":{\"name\":\"Jordan Journal of Chemistry\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2020-08-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jordan Journal of Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47014/15.1.4\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jordan Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47014/15.1.4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Synthesis of Some Pyrazole Derivatives from 5-Chloro- and 5-Azido-1,3-diphenyl-1H-pyrazole-4-carbaldehydes
N-[(5-Azido-1,3-diphenyl-1H-pyrazole-4-yl)methylene]-N-arylamines (4a-c) and N-[(5-Substituted-1,3-diphenyl-1H-pyrazole-4-yl)methylene]hydrazides (5a-e) were prepared from 5-azido-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (3) and 5-chloro-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (2), respectively. Thermolysis of (4a-c) and (5d-e) afforded 5-arylamino-1,3-diphenyl-1H-pyrazol-4-carbonitriles (8a-c) and N-(4-cyano-1,3-diphenyl-1H-pyrazol-5-yl)hydrazides (13a,b), respectively. N-[2-(5-Chloro-1,3-diphenyl-1H-pyrazol-4-yl)-4-oxo-thiazolidin-3-yl]amides (14a,b) and 3-acetyl-2-(5-chloro-1,3-diphenyl-1H-pyrazol-4-yl)-5-aryl-2,3-dihydro-1,3,4-oxadiazoles (15a,b) were obtained from N-[(5-chloro-1,3-diphenyl-1H-pyrazole-4-yl)methylene]hydrazides (5a,b). 5-Azido-1,3-diphenyl-1H-pyrazol-4-carbaldehyde (3) gave unexpectedly 1-(1,3-diphenyl-1,6-dihydropyrrolo-2,3-c]pyrazol-5-yl)ethan-1-one (17).
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