{"title":"核磁共振工具破译RNA的动态结构","authors":"Janghyun Lee, Byong-Seok Choi","doi":"10.6564/JKMRS.2017.21.2.055","DOIUrl":null,"url":null,"abstract":"It is now well established that RNAs exhibit fundamental roles in regulating cellular processes. Many of these RNAs do not exist in a single conformation. Rather, they undergo dynamic transitions among many different conformations to mediate critical interactions with other biomolecules such as proteins, RNAs, DNAs, or small molecules. Here, we briefly review NMR techniques that describe the dynamic behavior of RNA by determining structural, kinetic, and thermodynamic properties.","PeriodicalId":17414,"journal":{"name":"Journal of the Korean magnetic resonance society","volume":"21 1","pages":"55-62"},"PeriodicalIF":0.4000,"publicationDate":"2017-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"NMR Tools to Decipher Dynamic Structure of RNA\",\"authors\":\"Janghyun Lee, Byong-Seok Choi\",\"doi\":\"10.6564/JKMRS.2017.21.2.055\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"It is now well established that RNAs exhibit fundamental roles in regulating cellular processes. Many of these RNAs do not exist in a single conformation. Rather, they undergo dynamic transitions among many different conformations to mediate critical interactions with other biomolecules such as proteins, RNAs, DNAs, or small molecules. Here, we briefly review NMR techniques that describe the dynamic behavior of RNA by determining structural, kinetic, and thermodynamic properties.\",\"PeriodicalId\":17414,\"journal\":{\"name\":\"Journal of the Korean magnetic resonance society\",\"volume\":\"21 1\",\"pages\":\"55-62\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2017-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Korean magnetic resonance society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6564/JKMRS.2017.21.2.055\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Korean magnetic resonance society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6564/JKMRS.2017.21.2.055","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
It is now well established that RNAs exhibit fundamental roles in regulating cellular processes. Many of these RNAs do not exist in a single conformation. Rather, they undergo dynamic transitions among many different conformations to mediate critical interactions with other biomolecules such as proteins, RNAs, DNAs, or small molecules. Here, we briefly review NMR techniques that describe the dynamic behavior of RNA by determining structural, kinetic, and thermodynamic properties.
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