牛蒡的药用特性研究进展

IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Current Traditional Medicine Pub Date : 2023-04-28 DOI:10.2174/2215083810666230428095559
A. Wal, P. Wal, Vibha Shukla, Mohd Masih Uzzaman Khan, Khusboo Gaur, Nem Kumar Jain
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引用次数: 0

摘要

天然产物在药物分子的发现和开发中起着至关重要的作用。该植物的次生代谢产物具有潜在的治疗价值,并显示出许多药理作用。牛蒡是豆科草本植物,主要分布在印度、巴基斯坦、中国和阿富汗的干旱地区。Shinio、Bhip、Bhata、Ghugato和Ban Sutra只是它的几个名字。它用于治疗痛风、湿疹、狂犬病和炎症。植物根粥用于治疗伤寒、伤口和割伤、风湿病、胀气、耳痛、鼻出血和结石。这种植物的粉末状物用于消化障碍。该植物具有强大的药理活性,在自然界中也具有致癌和抗癌作用。存在各种植物成分,如单宁、氨基酸、生物碱、类固醇、三萜类、粘液、类黄酮、树胶、多酚、蒽醌、碳水化合物、糖苷和皂苷。Croburhine是从中提取的一种新的吡咯里嗪生物碱。本文综述了对C.burhia的植物化学和药理作用的现有知识,为正确评价该植物的药用价值提供了广泛的信息。综述了2005年至2022年对该属植物的实验分析和资料。各种数据库被用作文章来源,如Medline和Pubmed,并使用关键词Crotalaria burhia、栖息地、物种、药理作用和传统用途进行了文献综述。根据我们的认识,我们已经表明,禾谷属植物是一种具有强大药理活性的金黄色葡萄。它作为一种治疗各种疾病的常规药物被广泛使用,但其活性成分有待于进一步的药物开发和药理作用评估。共有21篇关于草药植物化学筛选的研究文章,显示了生物碱、单宁、黄酮类化合物、类固醇、糖苷、粘液、树胶、多酚、碳水化合物、萜类化合物等不同的活性成分的存在,这些成分对抗氧化、抗菌、抗炎、镇痛等不同的药理活性有反应,抗高血压、抗肿瘤和镇痛活性。
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Medicinal Properties of Crotalaria burhia: A Review
Natural products have a crucial role in the discovery and development of drug molecules. The secondary metabolites derived from the plant have potential therapeutic value and reveal many pharmacological effects. Crotalaria burhia Buchham, a Leguminaceae herb, is mostly present in arid parts of India, Pakistan, China, and Afghanistan. Shinio, Bhip, Bhata, Ghugato, and Ban Sutra are just a few of the names it goes by. It is used to cure gout, eczema, hydrophobia, and inflammation. Plant root porridge is used for typhoid, wounds and cuts, rheumatism, flatulence, earaches, nasal bleeding, and stone problems. The powder form of the plant is used for digestive disorders. The plant has potent pharmacological activity and is also carcinogenic and anticarcinogenic in nature. Various phytoconstituents are present, like tannins, amino acids, alkaloids, steroids, triterpenoids, mucilage, flavonoids, gum, polyphenols, anthraquinones, carbohydrates, glycosides, and saponins. Croburhine is a novel pyrrolizidine alkaloid obtained from it. This review focuses on the existing knowledge of the phytochemistry and pharmacological action of C. burhia, which will provide broad information for a proper assessment of the plant as a medicinal agent. The experimental analysis and data reported on the species of Crotalaria were reviewed from 2005 to 2022. Various databases were used as article sources, like Medline and Pubmed, and a literature review was done using the keywords Crotalaria burhia, habitat, species, pharmacological action, and traditional uses. On the basis of our perception, we have stated that the species Crotalaria burhia is a golden herb that possesses potent pharmacological activities. It is widely used as a conventional drug for the cure of various diseases, but its active constituents need to be evaluated more for future drug development and pharmacological action. There were a total of 21 research articles about the phytochemical screening of herbs, which showed the presence of different active constituents like alkaloids, tannins, flavonoids, steroids, glycosides, mucilage, gum, polyphenols, carbohydrates, terpenoids, etc., which are responsible for different pharmacological activities like antioxidant, antimicrobial, anti-inflammatory, antinociceptive, antihypertensive, antitumor, and analgesic activity.
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来源期刊
Current Traditional Medicine
Current Traditional Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
1.40
自引率
0.00%
发文量
91
期刊介绍: Current Traditional Medicine covers all the aspects of the modernization and standardization research on traditional medicine of the world, e.g. chemistry, pharmacology, molecular mechanism, systems biology, proteomics, genomics, metabolomics, safety, quality control, clinical studies of traditional Chinese, Ayurvedic, Unani, Arabic and other ethnomedicine. Each issue contains updated comprehensive in-depth/mini reviews along with high quality original experimental research articles. Current Traditional Medicine is a leading and important international peer-reviewed journal reflecting the current outstanding scientific research progresses of the global traditional, indigenous, folk and ethnologic medicine. It provides a bridge connected the tradition medicine system to the modern life science with the efforts of top scientists, as well as a resource to pursuit the solutions for the existing common issues in the traditional medicine.
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