胃肠道缺血- COVID-19患者的绊脚石

IF 1.5 Q3 GASTROENTEROLOGY & HEPATOLOGY Gastroenterology Insights Pub Date : 2022-06-14 DOI:10.3390/gastroent13020021
Monika Peshevska-Sekulovska, I. Boeva, M. Sekulovski, M. Zashev, M. Peruhova
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引用次数: 4

摘要

世界卫生组织(世界卫生组织)宣布新型SARS-CoV2病毒是造成疫情的罪魁祸首,这种病毒的出现让科学界和医学界措手不及。肺部疾病后最常见的并发症之一是胃肠道(GI)疾病,尤其是缺血性损伤。炎症、血管病变、不动、内皮功能障碍和高凝状态都被认为是这些患者胃肠道缺血的病理生理因素。由于新冠肺炎对各种胃肠道疾病的影响,特别是缺血性变化和高死亡率,医生应始终牢记这一并发症。他们应该更深入地研究这群患者的临床和影像学模式,以便应用适当且省时的治疗策略。我们的研究旨在阐明不同胃肠道疾病的血栓形成机制。此外,我们通过总结已经报道的新冠肺炎胃肠道缺血数据,分析了与坏死性胃肠道变化相关的因素。据我们所知,这篇综述是迄今为止首次纳入文献中报道的所有胃肠道缺血病例。
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Gastrointestinal Ischemia—Stumbling Stone in COVID-19 Patients
The emergence of the novel SARS-CoV2 virus, proclaimed by the World Health Organization (WHO) as a culpable agent for the pandemic situation, caught the scientific and medical communities off guard. One of the most common complications following pulmonary disease is represented by gastrointestinal (GI) disorders, especially ischemic damage. Inflammation, vasculopathy, immobility, endothelial dysfunction, and a hypercoagulable condition have all been proposed as pathophysiological factors for GI ischemia in these patients. Owing to the COVID-19 effect on a variety of GI conditions, especially ischemic changes, and the high mortality rate, physicians should always keep in mind this complication. They should take a deeper look at clinical and imaging modalities in this cohort of patients so that a proper and time-saving treatment strategy can be applied. Our study aimed to elucidate the thrombogenic mechanism in different GI disorders. Moreover, we analyzed the factors related to necrotic GI changes, by summarizing the already reported data of GI ischemia in COVID-19. To the best of our knowledge, this review is the first to incorporate all GI ischemia cases reported in the literature so far.
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来源期刊
Gastroenterology Insights
Gastroenterology Insights GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
2.80
自引率
3.40%
发文量
35
审稿时长
10 weeks
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