Sonia Singh, Bhupesh C. Semwal, Himanshu Sharma, D. Sharma
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Impact of Phytomolecules with Nanotechnology on the Treatment of
Inflammation
Inflammation is a part of the biological response of body tissues against harmful stimuli,
such as damaged cells, pathogens, irradiations, and toxic compounds. Numerous treatments, including anti-inflammatory drugs that treat the condition of inflammation, are available for its management. Because of the severe adverse effects associated with synthetic medications, phytotherapy
may be a promising and effective approach to treating inflammation. The therapeutic potential of
herbs is due to their capacity to target a variety of inflammatory mediators, including chemokines,
cytokines, nitric oxide, lipoxygenase, nuclear factor kappa-B, and arachidonic acid. Furthermore,
nanomedicine may be a valuable and effective formulation approach for overcoming the drawbacks
of phytoconstituents, such as their low bioavailability, high first-pass metabolism, and poor stability. The current manuscript provides a thorough description of many phytoconstituents and herbal
plants that have great potential for treating inflammation-related diseases, as well as information on
their limitations, drug formulations, and regulatory issues.
Current Bioactive CompoundsPharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.90
自引率
0.00%
发文量
112
期刊介绍:
The journal aims to provide comprehensive review articles on new bioactive compounds with proven activities in various biological screenings and pharmacological models with a special emphasis on stereoeselective synthesis. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia. The journal should prove to be essential reading for pharmacologists, natural product chemists and medicinal chemists who wish to be kept informed and up-to-date with the most important developments on new bioactive compounds of natural or synthetic origin, including their stereoeselective synthesis.