S. W. Shah, F. Ali, I. Bibi, Kashif Ali, Neelam Pervaiz, Mariyum Yousaf
{"title":"尿囊素-十八烯二酸二元体系的共晶形成与皮肤伤口愈合","authors":"S. W. Shah, F. Ali, I. Bibi, Kashif Ali, Neelam Pervaiz, Mariyum Yousaf","doi":"10.33640/2405-609x.3302","DOIUrl":null,"url":null,"abstract":"Abstract Eutectic formation in allantoin-octadecenedioic acid system (AOM) has been studied. The binary phase diagram revealed the existence of eutectic at X allantoin = 0.7. Dioic acid caused disruption of network in allantoin and induced defects, ultimately causing the reduction in crystallinity as shown by XRD and SEM analysis. The thermal stability in TGA graphs of allantoin was negligibly altered after mixture formation. Classical hydrogen bonding and alkyl interactions were predicted using software Avogadro and BIOVIA Discovery Studio. The functionalities involved in interactions taking place in the system were studied through in-depth FT-IR spectroscopy. The eutectic showed efficacy for cutaneous wound healing in oryctolagus cuniculus domesticus, hence it could be used as therapeutic for regulation and control of bioactivity.","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Eutectic Formation and Cutaneous Wound Healing by Binary Allantoin- Octadecenedioic Acid System\",\"authors\":\"S. W. Shah, F. Ali, I. Bibi, Kashif Ali, Neelam Pervaiz, Mariyum Yousaf\",\"doi\":\"10.33640/2405-609x.3302\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Eutectic formation in allantoin-octadecenedioic acid system (AOM) has been studied. The binary phase diagram revealed the existence of eutectic at X allantoin = 0.7. Dioic acid caused disruption of network in allantoin and induced defects, ultimately causing the reduction in crystallinity as shown by XRD and SEM analysis. The thermal stability in TGA graphs of allantoin was negligibly altered after mixture formation. Classical hydrogen bonding and alkyl interactions were predicted using software Avogadro and BIOVIA Discovery Studio. The functionalities involved in interactions taking place in the system were studied through in-depth FT-IR spectroscopy. The eutectic showed efficacy for cutaneous wound healing in oryctolagus cuniculus domesticus, hence it could be used as therapeutic for regulation and control of bioactivity.\",\"PeriodicalId\":17782,\"journal\":{\"name\":\"Karbala International Journal of Modern Science\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Karbala International Journal of Modern Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33640/2405-609x.3302\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Karbala International Journal of Modern Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33640/2405-609x.3302","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Eutectic Formation and Cutaneous Wound Healing by Binary Allantoin- Octadecenedioic Acid System
Abstract Eutectic formation in allantoin-octadecenedioic acid system (AOM) has been studied. The binary phase diagram revealed the existence of eutectic at X allantoin = 0.7. Dioic acid caused disruption of network in allantoin and induced defects, ultimately causing the reduction in crystallinity as shown by XRD and SEM analysis. The thermal stability in TGA graphs of allantoin was negligibly altered after mixture formation. Classical hydrogen bonding and alkyl interactions were predicted using software Avogadro and BIOVIA Discovery Studio. The functionalities involved in interactions taking place in the system were studied through in-depth FT-IR spectroscopy. The eutectic showed efficacy for cutaneous wound healing in oryctolagus cuniculus domesticus, hence it could be used as therapeutic for regulation and control of bioactivity.
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