{"title":"癌症恶病质治疗工具的功能评价综述","authors":"Lee Tang, John Jenn Yenn Lu, Sheau-Chung Tang","doi":"10.37290/ctnr2641-452x.21:187-193","DOIUrl":null,"url":null,"abstract":"Cachexia is a multifactorial and multi-organ condition that increases the mortality rate of patients with advanced cancer. Amelioration of cancer patients’ weight loss and inflammatory status are critical to the treatment’s success. Cachexia contains a significant drop in body weight and a rapid loss of lipoprotein, accompanied by an inflammatory state. In the late stage of cancer, anorexia and cachexia may occur at the same time, a condition called anorexia and cachexia syndrome. Keeping abreast of the patient’s inflammatory and nutritional status is of utmost importance for optimal treatment. This review explores the contribution of nutrient changes and the novel biomarker proteins in anorexia and cachexia syndrome. Functional assessment using anorexia and cachexia therapy assessment tools can monitor and provide early signals for anorexia and cachexia syndrome and suggest mechanism-based interventions to improve the status of cachexia with appropriate nutrients or drugs.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Functional Assessment of Therapy Tools for Cancer Cachexia: A Review\",\"authors\":\"Lee Tang, John Jenn Yenn Lu, Sheau-Chung Tang\",\"doi\":\"10.37290/ctnr2641-452x.21:187-193\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cachexia is a multifactorial and multi-organ condition that increases the mortality rate of patients with advanced cancer. Amelioration of cancer patients’ weight loss and inflammatory status are critical to the treatment’s success. Cachexia contains a significant drop in body weight and a rapid loss of lipoprotein, accompanied by an inflammatory state. In the late stage of cancer, anorexia and cachexia may occur at the same time, a condition called anorexia and cachexia syndrome. Keeping abreast of the patient’s inflammatory and nutritional status is of utmost importance for optimal treatment. This review explores the contribution of nutrient changes and the novel biomarker proteins in anorexia and cachexia syndrome. Functional assessment using anorexia and cachexia therapy assessment tools can monitor and provide early signals for anorexia and cachexia syndrome and suggest mechanism-based interventions to improve the status of cachexia with appropriate nutrients or drugs.\",\"PeriodicalId\":10976,\"journal\":{\"name\":\"Current Topics in Nutraceutical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Topics in Nutraceutical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.37290/ctnr2641-452x.21:187-193\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Topics in Nutraceutical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.37290/ctnr2641-452x.21:187-193","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
Functional Assessment of Therapy Tools for Cancer Cachexia: A Review
Cachexia is a multifactorial and multi-organ condition that increases the mortality rate of patients with advanced cancer. Amelioration of cancer patients’ weight loss and inflammatory status are critical to the treatment’s success. Cachexia contains a significant drop in body weight and a rapid loss of lipoprotein, accompanied by an inflammatory state. In the late stage of cancer, anorexia and cachexia may occur at the same time, a condition called anorexia and cachexia syndrome. Keeping abreast of the patient’s inflammatory and nutritional status is of utmost importance for optimal treatment. This review explores the contribution of nutrient changes and the novel biomarker proteins in anorexia and cachexia syndrome. Functional assessment using anorexia and cachexia therapy assessment tools can monitor and provide early signals for anorexia and cachexia syndrome and suggest mechanism-based interventions to improve the status of cachexia with appropriate nutrients or drugs.
期刊介绍:
Current Topics in Nutraceutical Research is an international, interdisciplinary broad-based peer reviewed scientific journal for critical evaluation of research on chemistry, biology and therapeutic applications of nutraceuticals and functional foods. The major goal of this journal is to provide peer reviewed unbiased scientific data to the decision makers in the nutraceutical and food industry to help make informed choices about development of new products.
To this end, the journal will publish two types of review articles. First, a review of preclinical research data coming largely from animal, cell culture and other experimental models. Such data will provide basis for future product development and/or human research initiatives. Second, a critical evaluation of current human experimental data to help market and deliver the product for medically proven use. This journal will also serve as a forum for nutritionists, internists, neurologists, psychiatrists, and all those interested in preventive medicine.
The common denominator of all of the topic to be covered by the journal must include nutraceuticals and/functional food. The following is an example of some specific areas that may be of interest to the journal. i) Role of vitamins, minerals, antioxidants and phytonutrients on cardiovascular health, cancer, diabetes, ocular health, mental health, men’s health, women’s health, infant nutrition, ii) Role of herbals on human health, iii) Dietary supplements and sleep, iv) Components of diet that may have beneficial effect on human health, v) regulation of apoptosis and cell viability, vi) Isolation and characterization of bioactive components from functional foods, vii) Nutritional genomics, and viii) Nutritional proteomics.