超重与肥胖成年男性最大自主通气量的比较研究

D. Harsh, Raghuveer Choudhary
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摘要

引言:肥胖是全球性的流行病。它的特点是体内脂肪堆积过多,通过各种机制影响包括呼吸系统在内的多个器官。全世界年轻人肥胖的患病率和严重程度都在增加。肺功能可以通过肺活量测定法来测定。最大自主通气测试评估呼吸耐力,并受肺部和胸部顺应性、呼吸控制和气道阻力的影响。目的:本研究的目的是比较肥胖、超重和非肥胖成年男性的最大自主通气参数,并评估肥胖对MVV的影响。方法:对拉贾斯坦邦西部年龄段18-25岁的76名成年男性进行了一项横断面研究,他们使用肺活量计进行了测量,根据体重指数(亚裔印度人的标准)进一步分为三组,根据WHR(腰臀比)分为两组。使用方差分析、Post-Hoc检验和线性回归检验对观察到的数据进行统计分析。结果:在我们的研究中,我们发现超重和肥胖的MVV值显著降低。肥胖男性MVV(L/Min)为68±10.80;超重男性为78.77±17.93,而非肥胖男性的相应值为112.61±19.42。根据方差分析,三组之间存在高度显著性(HS)差异(p 0.01)。多元回归方法显示与MVV呈高度显著性负相关(p<0.01)。结论:我们的研究得出结论,肺功能损害与成年超重和肥胖男性密切相关。通过减轻体重来降低BMI可以降低发病率。
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A Comparative Study of Maximum Voluntary Ventilation in Overweight & Obese Adult Males
Introduction : Obesity is a global ep idemic. It is characterized by excessive fat accumulation in the body, which affects multiple organs including the respiratory system by various mechanisms. The Prevalence and severity of obesity in young adults is increasing worldwide. The lung functions can be measured by spirometry. The Maximum Voluntary Ventilation test evaluates the respiratory endurance and is influenced by the lung and chest compliance, control of breathing and airway resistance. Aim : The purpose of this study was to compare the Maximum Voluntary Ventilation parameter in obese, overweight and non-obese adult males and to evaluate the impact of obesity on MVV. Methodology: A cross-sectional study was conducted among seventy-six adult males of Western Rajasthan in the age group ranging 18-25 years were performed on a spirometer, who were further divided into three groups based on Body Mass Index (criteria for Asian Indians) two groups based on WHR (waist-hip ratio). The observed data were statistically analyzed using ANOVA, Post-Hoc test and Linear Regression test. Results: In our study , we found a significant reduction in MVV values in overweight and obese. The obese males had MVV (L/Min) of 68 ± 10.80; overweight males of 78.77 ± 17.93 whereas corresponding values in non-obese were 112.61 ± 19.42. According to ANOVA, a highly-significant (HS) difference among the three groups (p˂0.01) . The multiple regression method reveals a negative correlation with MVV which is highly-significant (p<0.01) . Conclusion: Our study concluded that the impairment of Pulmonary Function is strongly associated with adult overweight and obese males. The reduction in BMI by reducing weight can reduce morbidity.
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