扩张型心肌病患者维生素D缺乏及其与心脏病严重程度的相关性

Gaur Kuldeep Kumar, Ghotekar Lh, Margekar Shubha Laxmi, K. Tarun, S. Ritu
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引用次数: 0

摘要

背景:心肌病主要是一种引起心肌功能障碍的心肌疾病,而不是其他心脏结构疾病或功能障碍、全身动脉高压、瓣膜狭窄或反流的结果。目的:本研究旨在确定扩张型心肌病(DCMP)患者维生素D缺乏的患病率及其与心脏病严重程度的相关性。方法:2019年11月至2021年10月,从新德里LHMC及其附属医院和ABVIMS & Dr. RML医院的内科/心内科招募70例经回声证实的DCMP病例。年龄大于18岁且愿意同意且不符合任何排除标准的DCMP患者被纳入本研究。结果:特发性DCMP患者平均年龄为48.3±15.2岁。男性48人(69%)多于女性22人(31%)。平均射血分数为26.6±7.3,平均缩短分数为17.6±3.1。90%的患者存在维生素D缺乏,其中68.5%为中度维生素D缺乏,10%为重度维生素D缺乏。结论:在我们的研究中,维生素D水平与DCMP患者心脏病的严重程度呈负相关。
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Vitamin D Deficiency and its Correlation with the Severity of Heart Disease in Dilated Cardiomyopathy Patients
Background: Cardiomyopathy is primarily a disorder of the cardiac muscle that causes myocardial dysfunction and is not the result of disease or dysfunction of other cardiac structures, systemic arterial hypertension and valvular stenosis or regurgitation. Aim: The present study aimed to determine the prevalence of vitamin D deficiency and its correlation with the severity of heart disease in patients with dilated cardiomyopathy (DCMP). Method: 70 ECHO-proven DCMP cases were enrolled from the medicine/ cardiology department of LHMC & associated hospitals and ABVIMS & Dr. RML Hospital, New Delhi from November 2019 to October 2021. DCMP patients with ages more than 18 years who were willing to give consent and does not meet any of the exclusion criteria were enrolled in this study. Results: Mean age of idiopathic DCMP patients was 48.3 ± 15.2. There were more males 48 (69%) than females 22 (31%). The mean ejection fraction was 26.6 ± 7.3, while the mean fractional shortening was 17.6 ± 3.1. Vitamin D deficiency was observed in 90% of patients, among which 68.5% were having moderate vitamin D deficiency and 10% were having severe vitamin D deficiency. Conclusion: In our study, vitamin D levels were inversely correlated with the severity of heart disease in DCMP patients.
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