{"title":"从儿科向成人医疗服务过渡后的头几年对围产期艾滋病毒感染青年的治疗依从性","authors":"P. Safonova, O. Koltsova","doi":"10.22328/2077-9828-2023-15-2-59-68","DOIUrl":null,"url":null,"abstract":"Objective. To assess ART adherence and treatment continuity in young adults living with HIV since birth or childhood in the first years after transition from paediatric to adult service of the AIDS Center, as well as to analyse factors associated with treatment adherence interruption after transition to adult care.Materials and methods. In our study, 86 cases of young people living with HIV since birth or childhood were obtained by chart audit and analyzed, among whom 53.5% were girls and 64.0% lived at home at the time of their 18th birthday, who have been transferred from paediatric to adult care of the AIDS Center for more than one year.Results and discussion. The majority (92%) of young adults living with HIV since birth or childhood retained in the health care system in the first year after the transition, but only 53–62% were highly adherent to treatment and monitoring for HIV infection in the first years after the transition. Episodes of non-adherence to treatment during childhood and adolescence, «more complex» ART scheme and the lack of adult’s social support at the time of 18th birthday increase the likelihood of interruption in treatment adherence in the first year after transition to adult care, while the combination of these factors has negative consequences for adherence and continuity of treatment for a longer period of time.Conclusion. Successful transition from paediatric to adult care for patients living with HIV since birth or childhood requires special additional attention of the health care system, contributes to the health protection of each patient, aims to stop HIV in the second generation.","PeriodicalId":37381,"journal":{"name":"HIV Infection and Immunosuppressive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adherence to treatment in young people with perinatal HIV infection in the first years after transition from pediatric to the adult medical service\",\"authors\":\"P. Safonova, O. Koltsova\",\"doi\":\"10.22328/2077-9828-2023-15-2-59-68\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective. To assess ART adherence and treatment continuity in young adults living with HIV since birth or childhood in the first years after transition from paediatric to adult service of the AIDS Center, as well as to analyse factors associated with treatment adherence interruption after transition to adult care.Materials and methods. In our study, 86 cases of young people living with HIV since birth or childhood were obtained by chart audit and analyzed, among whom 53.5% were girls and 64.0% lived at home at the time of their 18th birthday, who have been transferred from paediatric to adult care of the AIDS Center for more than one year.Results and discussion. The majority (92%) of young adults living with HIV since birth or childhood retained in the health care system in the first year after the transition, but only 53–62% were highly adherent to treatment and monitoring for HIV infection in the first years after the transition. Episodes of non-adherence to treatment during childhood and adolescence, «more complex» ART scheme and the lack of adult’s social support at the time of 18th birthday increase the likelihood of interruption in treatment adherence in the first year after transition to adult care, while the combination of these factors has negative consequences for adherence and continuity of treatment for a longer period of time.Conclusion. Successful transition from paediatric to adult care for patients living with HIV since birth or childhood requires special additional attention of the health care system, contributes to the health protection of each patient, aims to stop HIV in the second generation.\",\"PeriodicalId\":37381,\"journal\":{\"name\":\"HIV Infection and Immunosuppressive Disorders\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"HIV Infection and Immunosuppressive Disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22328/2077-9828-2023-15-2-59-68\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"HIV Infection and Immunosuppressive Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22328/2077-9828-2023-15-2-59-68","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Adherence to treatment in young people with perinatal HIV infection in the first years after transition from pediatric to the adult medical service
Objective. To assess ART adherence and treatment continuity in young adults living with HIV since birth or childhood in the first years after transition from paediatric to adult service of the AIDS Center, as well as to analyse factors associated with treatment adherence interruption after transition to adult care.Materials and methods. In our study, 86 cases of young people living with HIV since birth or childhood were obtained by chart audit and analyzed, among whom 53.5% were girls and 64.0% lived at home at the time of their 18th birthday, who have been transferred from paediatric to adult care of the AIDS Center for more than one year.Results and discussion. The majority (92%) of young adults living with HIV since birth or childhood retained in the health care system in the first year after the transition, but only 53–62% were highly adherent to treatment and monitoring for HIV infection in the first years after the transition. Episodes of non-adherence to treatment during childhood and adolescence, «more complex» ART scheme and the lack of adult’s social support at the time of 18th birthday increase the likelihood of interruption in treatment adherence in the first year after transition to adult care, while the combination of these factors has negative consequences for adherence and continuity of treatment for a longer period of time.Conclusion. Successful transition from paediatric to adult care for patients living with HIV since birth or childhood requires special additional attention of the health care system, contributes to the health protection of each patient, aims to stop HIV in the second generation.
期刊介绍:
In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.