巴西北部某皮肤科医院白癜风患者的临床和流行病学研究

A. L. Dias, C. Pires, Alvaro Alves dos Santos Neto, B. Oliveira, L. H. S. E. Silva, Thais Loyola da Silva, C. Mainardi, P. S. Franco, Maria Amélia Lopes dos Santos
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引用次数: 3

摘要

背景:白癜风是一种获得性低黑素病,影响世界人口的0.5%至4%,其特征是不同形状和大小的明显峰斑,可出现在皮肤的任何区域。在世界范围内,关于白癜风的出版物很少涉及流行病学特征。因此,目的是描述巴西北部贝尔萨姆市帕尔州立大学皮肤科诊所中患有这种疾病的患者的临床和流行病学概况。方法和发现:进行了一项横断面描述性研究,其中使用由与疾病相关的变量组成的方案分析了2000年7月至2014年7月在帕尔州立大学皮肤病诊所接受治疗的180例患者的医疗记录。所获得的资料被编入一个数据库,并提交给描述性和推断性统计分析。本研究经伦理与研究委员会批准,批准号为923.213。在成年年龄组(55%)中,以女性为主(72.2%);与家族史无关(46.7%);无进展(58.3%);临床以广泛性白癜风为主(67.2%),是常见的广泛性白癜风,患病率最高(57%)。发病部位主要为头颈部(27.5%)和上肢(25.3%)。结论:本研究揭示了居住在亚马逊地区的白癜风患者的特点,发现患者具有普遍的临床形式,大多数患者在建议的治疗下病变得到改善,只有少数患者出现疾病进展。结论:白癜风是一种治疗难度较大的疾病,强调早期诊断的重要性,因为在早期阶段更容易解决疾病。
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Clinical and Epidemiological Study of Vitiligo Patients at a Dermatology Service in Northern Brazil
Background: Vitiligo is an acquired hypomelanosis that affects between 0.5% and 4% of the world population, characterized by distinct acromic macules of various shapes and sizes, and may appear in any region of the skin. Worldwide, there are few publications on vitiligo that address epidemiological characteristics. Thus, the objective was to describe the clinical and epidemiological profile of patients with this condition at the State University of Pará’s Dermatology Clinic, in the city of Belém, Northern of Brazil. Methods and Findings: A cross-sectional descriptive study was performed, in which 180 medical records of patients treated at the State University of Pará’s Dermatology Clinic, from July 2000 to July 2014, were analyzed using a protocol consisting of variables related to the disease. The information obtained was organized in a database and submitted to descriptive and inferential statistical analysis. The study was approved by the ethics and research committee under the number 923.213. A predominance of the female gender (72.2%), of the adult age group (55%) was observed; without relation to family history (46.7%); without progression (58.3%); with a predominant clinical form of vitiligo of the generalized type (67.2%), being the common generalized one with the highest prevalence (57%). The most affected sites were head and neck (27.5%), and upper limbs (25.3%). Conclusions: This study revealed the characteristics of the vitiligo patient residing in the Amazon region, and patients were found to have a generalized clinical form, most of the patients achieved improvement of the lesions with the proposed treatment, and only a minority presented progression of the disease. It is concluded that vitiligo is a disease with great therapeutic difficulty, and it is emphasized the importance of an early diagnosis, since in the early stages is easier to resolve the disease.
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