牛Tunica阴道粉预防雄鹿肌腱修复过程中肌腱粘连的效果

A. Khudair, Hassanain A. Emran
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引用次数: 0

摘要

本研究旨在研究冻干牛阴道膜粉对山羊指浅屈肌腱(SDFT)诱导性缺损腱周粘连的影响。这项研究是在18只成年雄鹿身上进行的,手术是在高度无菌的条件下进行的。手术前,通过肌肉注射剂量为0.5 mg/kg体重的2%甲苯噻嗪使动物镇静,然后通过2%盐酸利多卡因的线性渗透麻醉手术部位。在左前肢掌骨掌表面的皮肤上进行手术切口,以暴露(SDFT),在暴露的肌腱上形成(0.1深,0.2宽,1长)cm的缺损,在(9)只动物中用无菌生理盐水滴填充该间隙,并作为对照组提及,而其余(9)只动物的间隙被作为处理组的冻干粉填充。皮下组织采用可吸收缝合材料通过简单连续缝合技术闭合,并采用非吸收缝合材料的简单间断缝合垫闭合皮肤。宏观检查结果显示,第一组和第二组在术后第二和第三个评估期的粘附得分存在显著差异,各组之间没有显著差异。本研究的结论是,鞘膜支架对减少肌腱与周围组织之间的粘附没有明显作用。
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Effectiveness of Bovine Tunica Vaginalis Powder in the Prevention of Tendon Adherence Following Tendon Repair Process in Bucks
The current study was designed to investigate the efficacy of lyophilized bovine tunica vaginalis powder on peritendinous adhesion of induced defect in superficial digital flexor tendon (SDFT) in goats. The study was carried out on 18 adult bucks, the surgical procedure was done under highly aseptic conditions. Prior to surgery, animals were sedated by intramuscular injection of 2 % xylazine in a dose 0.5 mg/kg body weight, then the site of the operation is anesthetized by linear infiltration of 2% lidocaine hydrochloride. The surgical incision is made on the skin on the palmer surface of the metacarpal bone of the left forelimb to expose the (SDFT), a (0.1 depth, 0.2 width, and l Long) cm defect is made on the exposed tendon, this gap is filled with drops of sterile normal saline in (9) animals, and mentioned as a control group, while the gap of the rest (9) animals is filled with the lyophilized powder as treated group. Subcutaneous tissue was closed using absorbable suture material by simple continuous suture technique, and a simple interrupted suture mattress using non-absorbable suture material for closing the skin. The macroscopic findings exhibited a significant difference in adhesion scores between the 2nd, and 3rd periods of assessment post-operation in the first and second groups, with no significant differences between groups. The conclusion of this study is the tunica vaginalis scaffold has no obvious effect on decreasing adhesion between a tendon and surrounding tissues.
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