Peripheral edema associated with low dose of pregabalin in an older person

Peripheral edema has been reported as an adverse effect of various medications including antibiotics, nonsteroidal anti-inflammatory drugs, anti-hypertensive drugs, antipsychotics, etc., There are a limited number of cases reported the association of a high dose of Pregabalin association with peripheral edema, but none of them reported the low dose association with peripheral edema. We report a case of an older person presented with depressive disorder, had peripheral edema with 50 mg of pregabalin. It is suggested that a clinician should be aware of this association. Geriatrician should be careful when advising the pregabalin to an older person.