结直肠癌的姑息治疗

IF 2.7 Q3 ONCOLOGY Colorectal Cancer Pub Date : 2020-09-24 DOI:10.5772/INTECHOPEN.93513
R. Caponero
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引用次数: 0

摘要

大约25%的患者在首次诊断时出现肝转移,高达50%的患者在病程中会进一步发展为肝脏复发。传统的手术方法,通过切除原始肿瘤或造口,在过去三十年中,对无法治愈的第四期癌症大肠癌患者的治疗发生了显著变化,目前是多学科的,化疗发挥了关键作用。大多数癌症IV期患者预后不良,但目前有许多姑息治疗方法。当无法治愈时,治疗的方向是提供症状缓解。肿瘤学中良好的症状管理与患者和家庭生活质量的提高、治疗依从性的提高有关,甚至可能提供生存优势。
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Palliative Care in Colorectal Cancer
Approximately 25% of patients present with liver metastases at the time of the first diagnosis and up to 50% will further develop recurrence in the liver during their disease course. Traditionally approached surgically, by resection of the primitive tumor or stoma, the management to incurable stage IV colorectal cancer patients has significantly changed over the last three decades and is nowadays multidisciplinary, with a pivotal role played by chemotherapy. Most patients with stage IV colorectal cancer have a poor prognosis, but numerous palliative modalities are available today. When a cure is no longer possible, treatment is directed toward providing symptomatic relief. Good symptom management in oncology is associated with improved patient and family quality of life, greater treatment compliance, and may even offer survival advantages.
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来源期刊
Colorectal Cancer
Colorectal Cancer ONCOLOGY-
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期刊介绍: Colorectal cancer is a major cause of morbidity and mortality, particularly in the developed world. Risk factors for colorectal cancer are on the rise in many countries; populations are aging, and obesity and diabetes are increasing. National screening programs are helping to detect cancer while it is still curable; however, colorectal cancer remains the third leading cause of cancer deaths in the USA and options are still limited for those with more advanced disease. Consequently, colorectal cancer is a major research priority for government, pharmaceutical companies and non-profit organizations. Research into diagnosis and optimum treatment of the disease is progressing rapidly, with new advances reported every day. Colorectal Cancer presents reviews, analysis and commentary. on all aspects of colorectal cancer.
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