{"title":"双侧大体积肾上腺浆细胞瘤，对达拉图单抗治疗有很好的反应","authors":"Fang Wang, Han-Kuang Hsieh, Tso-fu Wang, Yi-Feng Wu","doi":"10.4103/ejcrp.eJCRP-D-22-00027","DOIUrl":null,"url":null,"abstract":"Extramedullary myeloma disease represents an infrequent but aggressive variant of multiple myeloma (MM), and it is associated with a poor prognosis. An optimal treatment strategy for this clinical subset has not yet been clarified. In this report, we demonstrate a patient with MM with the uncommon manifestation of plasmacytomas with a very high burden in the bilateral adrenal glands at diagnosis, which were treated successfully with daratumumab-based second-line therapy.","PeriodicalId":31219,"journal":{"name":"Journal of Cancer Research and Practice","volume":"10 1","pages":"78 - 81"},"PeriodicalIF":0.0000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bilateral bulky adrenal plasmacytomas with very good response to daratumumab-based therapy\",\"authors\":\"Fang Wang, Han-Kuang Hsieh, Tso-fu Wang, Yi-Feng Wu\",\"doi\":\"10.4103/ejcrp.eJCRP-D-22-00027\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Extramedullary myeloma disease represents an infrequent but aggressive variant of multiple myeloma (MM), and it is associated with a poor prognosis. An optimal treatment strategy for this clinical subset has not yet been clarified. In this report, we demonstrate a patient with MM with the uncommon manifestation of plasmacytomas with a very high burden in the bilateral adrenal glands at diagnosis, which were treated successfully with daratumumab-based second-line therapy.\",\"PeriodicalId\":31219,\"journal\":{\"name\":\"Journal of Cancer Research and Practice\",\"volume\":\"10 1\",\"pages\":\"78 - 81\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cancer Research and Practice\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/ejcrp.eJCRP-D-22-00027\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cancer Research and Practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ejcrp.eJCRP-D-22-00027","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Bilateral bulky adrenal plasmacytomas with very good response to daratumumab-based therapy
Extramedullary myeloma disease represents an infrequent but aggressive variant of multiple myeloma (MM), and it is associated with a poor prognosis. An optimal treatment strategy for this clinical subset has not yet been clarified. In this report, we demonstrate a patient with MM with the uncommon manifestation of plasmacytomas with a very high burden in the bilateral adrenal glands at diagnosis, which were treated successfully with daratumumab-based second-line therapy.
期刊介绍：
JCRP aims to provide an exchange forum for the cancer researchers and practitioners to publish their timely findings in oncologic disciplines. The scope of the Journal covers basic, translational and clinical research, Cancer Biology, Cancer Immunotherapy, Hemato-oncology, Digestive cancer, Urinary tumor, Germ cell tumor, Breast cancer, Lung cancer, Head and Neck Cancer in a vast range of cancer related topics. The Journal also seeks to enhance and advance the cancer care standards in order to provide cancer patients the best care during the treatments.
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