COVID-19研究,公共卫生和生物医学基础

IF 0.3 Q4 PHARMACOLOGY & PHARMACY Current Drug Therapy Pub Date : 2023-08-01 DOI:10.2174/1574885518666230801091246
Da Yong Lu, Ting Ren Lu
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引用次数: 0

摘要

新型冠状病毒疫情(COVID-19, SARS-CoV-2)对世界产生了巨大影响。尽管在生物医学方面做出了巨大努力,但全球约有30-50%的人口至少感染过一次COVID。全球范围内的COVID-19流行病降低了人类的预期寿命。尽可能有效地预防和治疗COVID-19是必不可少的。为了更好地预防和治疗冠状病毒感染,需要更新临床诊断或治疗模式。各地区、各国疫情防控的外部条件不平衡,应着眼于全球防控行动。尽管全球接种了COVID疫苗,但仍有很大一部分人不断接触和感染病毒。先进的病毒生物学知识和疫苗技术可以减轻病毒的传播,促进治疗。应该设计、整合和引入普遍和具体的预防和治疗范例。COVID-19的起源和隐蔽性、生物学和发病机制已被广泛了解。病毒疫苗、发病机制、诊断、治疗和个性化医疗正在迅速发展。许多病毒疫苗和个性化医疗应特别强调。为加快全球抗击COVID-19的努力,讨论了病毒传播的新知识和突破、疫苗技术创新、诊断范围扩大和全球治疗变异性。不同的战略平台和景观可以达到不同的结果。通过促进针对不同变体COVID的全球机制,可以减少病毒引起的社会经济负担和不平衡。
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COVID-19 Research, Public Health, and Biomedical Basis
The coronavirus outbreak (COVID-19, SARS-CoV-2) greatly impacts the world. Despite great biomedical efforts, approximately 30-50% global population was at least once infected with COVID. Human life expectancy is reduced by COVID-19 epidemics worldwide. It is indispensable to prevent and treat COVID-19 as effectively as possible. In order to well prevent and treat the coronavirus infection, clinical diagnostic or therapeutic paradigms should be updated. Since the outside condition of COVID-19 prevention is imbalanced among regions and countries, global prevention and treatment action should be aimed. Despite global vaccination for COVID, a significant proportion of humans still constantly exposes and infected with viruses. Advanced viral biological knowledge and vaccine techniques can alleviate viral spread and promote therapeutics. Universal and specific preventive and treatment paradigms should be designed, integrated, and introduced. The origin and hidden nature of COVID-19 biology and pathogenesis are broadly understood now. Viral vaccines, pathogenesis, diagnosis, treatment, and personalized medicine are progressing rapidly. Many viral vaccines and personalized medicine should be especially emphasized. To speed up global efforts against COVID-19, new knowledge and breakthroughs of viral transmissibility, vaccine technique innovation, diagnostic widening, and therapeutic variability worldwide are discussed. Different strategic platforms and landscapes can reach different outcomes. By facilitating global machinery against different variants of COVID, viral-induced socioeconomic burden and imbalance could be reduced.
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来源期刊
Current Drug Therapy
Current Drug Therapy PHARMACOLOGY & PHARMACY-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
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