伊朗伊拉姆市输血中心志愿献血者中HIV、乙型肝炎和丙型肝炎感染率

H. Boustani, E. Anvari, Sedighe Saiadi Sartang, M. Omidi, E. Rostami, Zahra Mohamadi
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引用次数: 7

摘要

简介:多年来,血液制品一直被认为是一种有效的治疗方法。然而,这种治疗并非没有感染传播的风险,包括接受血液治疗的人中的乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和人类免疫缺陷病毒(HIV)。尽管如此,由于输血导致血液传播疾病的风险很高,根据世界卫生组织(世界卫生组织)的规定,对这些病毒进行筛查是强制性的。本研究的主要目的是评估伊拉姆献血中心(BDCI)健康献血者中HBV、HCV和HIV感染的患病率。材料和方法:在本研究中,我们使用了2009年2月至2013年1月期间首次和多次转诊BDCI的献血者的信息。提取献血者的人口学特征,包括婚姻状况、年龄、性别和献血模式。对HBV、HIV和HCV进行常规供体实验室筛查。结果:HBV感染率最高(0.14%),HIV感染率最低(0.006%),男性献血者感染率最高。男性和初次献血者中HBv、HIV和HCV感染率较高(P<0.01),已婚献血者中HIV和HCV的感染率高于单身献血者(P<0.01);单身献血者中HBv感染率高于已婚献血者(P<0.05)。HBV、HCV和HIV感染率最高和最低的受试者分别在51至60岁和18-35岁之间。结论:据估计,自愿献血者的HBV、HCV和HIV感染率低于普通人群,这证实了献血者教育和检查的有效性。这通常源于捐赠前对高危行为的筛查,因此删除高危人群。由于不安全的血液制品不用于输血,它们不被视为血液安全系统的风险,但这些血液单位的识别是输血中心的一个问题。
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Prevalence of HIV, hepatitis B and C infections among volunteer blood donors at the blood transfusion center of Ilam city, Iran
Introduction: Blood derived products have been known as an effective treatment for many years. However, this treatment is not without risk of infections transmission including hepatitis B virus (HBV) and hepatitis C virus (HCV) and human immune-deficiency virus (HIV) in people who received the blood. Nevertheless, due to a high risk of blood born diseases through blood transfusion, screening for these viruses according to the World Health Organization (WHO) is mandatory. The main aim of this research was to assess the prevalence of HBV, HCV and HIV infections among healthy blood donors of Blood Donor Center of Ilam (BDCI). Materials and methods: In this study we used the information from first and repeated blood donors who referred to BDCI within February 2009 to January 2013. Demographic characteristics of donors including marital status, age, gender and blood donation pattern was extracted. Routine donor laboratory screening tests for HBV, HIV and HCV were performed. Results: HBV infection had the highest prevalence (0.14%) while HIV had the lowest ones (0.006%). The highest prevalence was among male blood donors. The prevalence of HBv, HIV and HCV infections were more common among men and first time donors (P < 0.01). The prevalence of HIV and HCV infections were more common among married donors than singe ones (P < 0.01) HBV prevalence in singles was more (P < 0.05) compared to married blood donors. The highest and the lowest subjects with HBV, HCV and HIV infections were in range of 51 to 60 years and 18-35 years old, respectively. Conclusion: It is estimated that the prevalence of HBV, HCV and HIV infections are low in voluntary blood donors than general population which confirmed the effectiveness of education and examination of blood donors. This usually arising from the pre donation screening for risky behaviors, so deleting the high risk people. Since unsafe blood products are not used for blood transfusion, they are not considered as risk for blood safety system, but identification of these blood units is a problem for blood transfusion centers.
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