皮质综合疗法治疗脑震荡后综合征及轻度外伤性脑损伤的疗效观察

V. M. Pedro, Nicole C H Lim, E. Oggero
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摘要

脑震荡后综合症(PCS)是一种相对普遍的状况,出现在持续的头部损伤。患有PCS的个体会经历与损伤相关的长期损伤和痛苦,这可能会影响个体的生活质量。在这项对诊断为PCS和轻度外伤性脑损伤(mTBI)的难治性成人患者的回顾性图表回顾中,通过比较PedroCIT®前后获得的体位稳定性、大脑测序和时间以及PCS的身体和心理社会症状的自我报告,研究了皮质综合疗法(PedroCIT®)的有效性。多元和重复测量一般线性模型显示,所有受试者在治疗前后的测量均有所改善,突出了PedroCIT®的有效性。为了进一步强调PedroCIT®对在PedroCIT®之前对治疗有耐药性的患者的改善能力,将受试者接受PedroCIT®治疗的持续时间与受试者首次接受PedroCIT®干预后受伤的持续时间进行了比较。这项研究的结果显示,从治疗前到治疗后,受PCS和mTBI影响的患者在姿势稳定性、大脑测序和时间以及自我报告的症状方面都有显著改善,治疗结果在很大程度上不取决于治疗开始时病情的严重程度。总之,这项回顾性研究表明,受PCS和mTBI影响的难治性个体可以从接受PedroCIT®治疗中获益,他们的治疗结果可能与治疗开始时出现的损害程度无关。
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CORTICAL INTEGRATIVE THERAPY EFFECTIVENESS IN THE TREATMENT OF POST-CONCUSSION SYNDROME AND MILD TRAUMATIC BRAIN INJURY
Post-Concussion Syndrome (PCS) is a relatively prevalent condition that emerges after sustaining a head injury. Individuals with PCS experience prolonged impairments and distress associated with the injury which can impact the individuals’ quality of life experiences. In this retrospective chart review of refractory adult patients diagnosed with PCS and mild Traumatic Brain Injury (mTBI), the effectiveness of Cortical Integrative Therapy (PedroCIT®) was investigated by comparing measures of postural stability, brain sequencing and timing, and self-reports of physical and psychosocial symptoms of PCS obtained before and after PedroCIT®. Multivariate and Repeated Measures General Linear Models showed improvements across the measures from before to after treatment in all subjects, highlighting the effectiveness of PedroCIT®. To further underscore the capacity of PedroCIT® to elicit improvements in patients who have been resistant to treatment prior to PedroCIT®, the duration of time that the subjects underwent PedroCIT® was compared to the duration of time since the injury to the subjects’ first PedroCIT® intervention session. The findings of this study showed significant improvements from pre- to post-treatment in postural stability, brain sequencing and timing, and self-reported symptoms for patients affected by PCS and mTBI, and treatment outcomes were largely not contingent upon the severity of the condition at the beginning of treatment. Altogether, this retrospective study suggests that refractory individuals affected by PCS and mTBI can benefit from undergoing PedroCIT® and their treatment outcomes may not be related to the degree of impairment presented at the beginning of treatment.
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