{"title":"重复经颅磁刺激(rTMS)减少赌博障碍患者的赌博渴望:对高级临床研究的呼吁","authors":"C. Okechukwu","doi":"10.15540/NR.8.1.69","DOIUrl":null,"url":null,"abstract":"Gambling disorder (GD) is an addictive behavioral disorder that alters the frontostriatal neural circuitry and prefrontal control of reward-associated brain areas. An intrusion between prefrontal cortex and the mesolimbic reward pathway has been proposed as the major mechanism behind the pathogenesis of GD. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment that utilizes magnetic fields to stimulate nerve cells linked to mood and behavioral control; this stimulation is usually applied either on the left or right side of the dorsolateral prefrontal cortex of the brain. rTMS selectively modulates the activities of brain circuits and possess the ability to overturn the alterations in the neurocircuitry of the brain linked to the pathophysiology of GD. rTMS adjusts impulsivity, cognitive/attentional control, cognitive plasticity, and decision-making, which are crucial in decreasing gambling craving and relapse. However, innovative clinical investigations are needed to analyze and establish the impact of rTMS on gambling craving and cessation, using a larger sample size.","PeriodicalId":37439,"journal":{"name":"NeuroRegulation","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Repetitive Transcranial Magnetic Stimulation (rTMS) for Decreasing Gambling Craving in Patients with Gambling Disorder: A Call for Advanced Clinical Investigations\",\"authors\":\"C. Okechukwu\",\"doi\":\"10.15540/NR.8.1.69\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gambling disorder (GD) is an addictive behavioral disorder that alters the frontostriatal neural circuitry and prefrontal control of reward-associated brain areas. An intrusion between prefrontal cortex and the mesolimbic reward pathway has been proposed as the major mechanism behind the pathogenesis of GD. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment that utilizes magnetic fields to stimulate nerve cells linked to mood and behavioral control; this stimulation is usually applied either on the left or right side of the dorsolateral prefrontal cortex of the brain. rTMS selectively modulates the activities of brain circuits and possess the ability to overturn the alterations in the neurocircuitry of the brain linked to the pathophysiology of GD. rTMS adjusts impulsivity, cognitive/attentional control, cognitive plasticity, and decision-making, which are crucial in decreasing gambling craving and relapse. However, innovative clinical investigations are needed to analyze and establish the impact of rTMS on gambling craving and cessation, using a larger sample size.\",\"PeriodicalId\":37439,\"journal\":{\"name\":\"NeuroRegulation\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"NeuroRegulation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15540/NR.8.1.69\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"NeuroRegulation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15540/NR.8.1.69","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Repetitive Transcranial Magnetic Stimulation (rTMS) for Decreasing Gambling Craving in Patients with Gambling Disorder: A Call for Advanced Clinical Investigations
Gambling disorder (GD) is an addictive behavioral disorder that alters the frontostriatal neural circuitry and prefrontal control of reward-associated brain areas. An intrusion between prefrontal cortex and the mesolimbic reward pathway has been proposed as the major mechanism behind the pathogenesis of GD. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment that utilizes magnetic fields to stimulate nerve cells linked to mood and behavioral control; this stimulation is usually applied either on the left or right side of the dorsolateral prefrontal cortex of the brain. rTMS selectively modulates the activities of brain circuits and possess the ability to overturn the alterations in the neurocircuitry of the brain linked to the pathophysiology of GD. rTMS adjusts impulsivity, cognitive/attentional control, cognitive plasticity, and decision-making, which are crucial in decreasing gambling craving and relapse. However, innovative clinical investigations are needed to analyze and establish the impact of rTMS on gambling craving and cessation, using a larger sample size.
期刊介绍：
NeuroRegulation is a peer-reviewed journal providing an integrated, multidisciplinary perspective on clinically relevant research, treatment, reviews, and public policy for neuroregulation and neurotherapy. NeuroRegulation publishes important findings in these fields with a focus on electroencephalography (EEG), neurofeedback (EEG biofeedback), quantitative electroencephalography (qEEG), psychophysiology, biofeedback, heart rate variability, photobiomodulation, repetitive Transcranial Magnetic Simulation (rTMS) and transcranial Direct Current Stimulation (tDCS); with a focus on treatment of psychiatric, mind-body, and neurological disorders. In addition to research findings and reviews, it is important to stress that publication of case reports is always useful in furthering the advancement of an intervention for both clinical and normative functioning. We strive for high quality and interesting empirical topics presented in a rigorous and scholarly manner. The journal draws from expertise inside and outside of the International Society for Neurofeedback & Research (ISNR) to deliver material which integrates the diverse aspects of the field, to include: *basic science *clinical aspects *treatment evaluation *philosophy *training and certification issues *technology and equipment
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