HTO和UKA治疗膝关节骨性关节炎的Meta分析

Lei Zhang, Mubin Wei, Aifeng Liu, Shuwei Gong, Zhi-ping Tu
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引用次数: 1

摘要

目的应用Meta分析评价胫骨高位截骨(HTO)和单室膝关节置换术(UKA)治疗膝关节单室骨关节炎(KOA)的疗效。方法检索HTO和UKA治疗KOA的对照临床试验文献,数据库包括中国生物医学文献数据库、万方数据、CNKI、VIP数据、PubMed、Cochrane Library、EBSCO和Embase,检索期为数据库开始至2018年7月。对文献进行筛选和评估,并使用Review Manager 5.3软件进行荟萃分析。结果共收录19篇文章,包括1359个膝关节。Meta分析结果显示,HTO在运动范围(ROM)上优于UKA(P 0.05)。结论HTO和UKA各有优缺点。要根据患者的病情和心理预期,适当选择手术方式。关键词:胫骨高位截骨;单室膝关节置换术;单室膝骨关节炎;Meta分析
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Comparison of HTO and UKA in the treatment of unicompartmental knee osteoarthritis: a Meta analysis
Objective To evaluate the efficacy of high tibial osteotomy(HTO) and unicompartmental knee arthroplasty(UKA) for knee unicompartmental osteoarthrits(KOA) using Meta analysis. Methods The controlled clinical trial literatures of HTO and UKA treating KOA were retrieved, the database including Chinese Biomedical Literature Database, Wanfang Data, CNKI, VIP Data, PubMed, Cochrane Library, EBSCO and Embase, and the search period was limited to the beginning of the database to July 2018. The literature was screened and evaluated, and Review Manager 5.3 software was used for Meta analysis. Results A total of 19 articles including 1 359 knee joints were included. Meta analysis results showed that HTO was superior to UKA in range of motion (ROM) (P 0.05). Conclusions Both HTO and UKA have their own advantages and disadvantages. It is necessary to properly choose the operation according to the patient's condition and psychological expectation. Key words: High tibal osteotomy; Unicompartmental knee arthroplasty; Unicompartmental knee osteoarthritis; Meta analysis
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