抗肿瘤药用植物的重要作用

Q4 Agricultural and Biological Sciences Proceedings of the Pakistan Academy of Sciences: Part B Pub Date : 2023-09-08 DOI:10.53560/ppasb(60-3)847
Iram Asim, Muhammad Ikrama Tanveer, Humaira Yasmeen
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引用次数: 0

摘要

在医疗系统中,药用植物一直占有重要地位。具有已知生物活性的植物化学物质,如抗病毒、抗菌和抗癌特性,在治疗中至关重要。近年来,它几乎没有负面影响,被认为是安全的。药用植物的使用对于预防疾病至关重要,尤其是癌症,它是全球第二大死亡原因。到目前为止,科学家们已经有效地发现了抗癌化合物,如丁香酚、大蒜素、儿茶素、姜黄素熊果酸、茴香酚、番茄红素、白藜芦醇、来自姜、番茄、大蒜、姜黄、蓝莓、奶蓟、蔓越莓、胡桃的6-姜酚,这些化合物可以帮助阻断或激活癌症细胞激活途径,基质金属蛋白酶MMP、COX-2、拓扑异构酶、Bax、Bak蛋白和保护身体的加速酶(抗氧化潜力)。癌症目前使用一些植物性产品及其植物成分进行治疗。尽管癌症进展的管理和控制取得了显著进展,但仍有许多差距和未开发的前景。因此,这篇综述文章强调了药用植物在维持人类健康方面的价值,并列出了药用植物中可用于治疗癌症的植物化学物质。
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Significant Role of Medicinal Botanicals Hostile to Cancer
In medical systems, medicinal plants have always held an important place. Plant phytochemicals with known biological activity, such as antiviral, antibacterial, and anticancer properties, are crucial in treatment. It has demonstrated little to no negative effects in recent years and is regarded as safe to use. The use of medicinal plants is essential for preventing illnesses, especially cancer, which is the second leading cause of death worldwide. It was discovered that scientists had been effective in finding anti-cancer compounds up to this point such as eugenol, allicin, catechins, curcumin ursolic acid, anethol, lycopene, resveratrol, 6-gingerol from ginger, tomato, garlic, turmeric, blueberries, milk thistle, cranberries, walnuts which can assist in blocking or activating cancer cell activation signalling pathways cycloxigenase, matrix metalloproteinases MMP, COX-2, topoisomerase enzyme, Bax, Bak proteins and accelerating enzymes (antioxidant potential) that protect the body. Cancer is now treated with a few plant-based products and their phytoconstituents. Even though the management and control of cancer progression have advanced significantly, there are still many gaps and untapped prospects. As a result, this review article emphasizes the value of medicinal plants in maintaining human health as well as lists the phytochemicals from medicinal plants that can be used to cure cancer.
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来源期刊
Proceedings of the Pakistan Academy of Sciences: Part B
Proceedings of the Pakistan Academy of Sciences: Part B Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)
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