先天性心脏病矫正后意外感染性心内膜炎1例报告

C. J. Cool, Rachmi Serulina, Aninka Saboe
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摘要

目的:描述先天性心脏病(CHD)患者并发感染性心内膜炎(IE)的情况。方法:2019年观察2例IE。第一个病例涉及一名36岁的女性,在入院前四个月曾经皮经导管膜周室间隔缺损(VSD)封堵。超声心动图显示主动脉瓣非冠状尖端有植被。患者接受了六周的抗生素治疗,并接受了植被和装置的清除手术,同时用心血管贴片(Gore-tex)闭合VSD。第二个病例涉及一名43岁的女性,她有在入院前两个月通过心包补片封堵继发性房间隔缺损(ASD)的病史。超声心动图显示三尖瓣有植被。患者接受了为期四周的抗生素治疗,并计划进行手术以清除植被。结果:IE是CHD的主要并发症之一,无论是未纠正、治疗还是纠正。侵入性手术增加了IE的风险。关闭后IE是罕见的。不良的牙齿卫生和免疫功能低下也增加了患者暴露于IE的风险,如第一名患有龋齿的患者和第二名接受甲基强的松龙术后心包积液治疗的患者所示。结论:冠心病患者发生IE的风险随着有创手术的进行而增加。尽管IE的发病率非常罕见,但其可能性应该引起医生的严重关注。
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Unexpected Infective Endocarditis in Corrected Congenital Heart Disease: A Case Report
Objective: To describe patients with corrected Congenital Heart Disease (CHD) who experienced Infective Endocarditis (IE). Methods: Two cases of IE were observed in 2019. The first case involved a 36-year-old woman with previous percutaneous transcatheter perimembranous ventricular septal defect (VSD) closure four months before admission. Echocardiography showed vegetation at noncoronary cusps of the aortic valve. Patient received antibiotics for six weeks and underwent surgery for evacuation of vegetation and device, along with VSD closure with a cardiovascular patch (Gore-tex). The second case involved a 43-year-old woman with a history of surgical closure in secundum atrial septal defect (ASD) by pericardial patch two months before admission. Echocardiography showed vegetation at the tricuspid valve. Patient received antibiotics for four weeks and planned for surgery to evacuate vegetation. Results: IE is one of the major complications in CHD, whether uncorrected, treated, or corrected. The risk of IE increased with an invasive procedure. Post closure IE is rare. Poor dental hygiene and immunocompromised also increased patient's risk to be exposed to IE as shown in the first patient who had dental caries and the second patient who was on methylprednisolone for post-surgical pericardial effusion treatment. Conclusion: The risk of IE increases with invasive procedures in CHD patients. Although the incidence of IE is quite rare, its possibility should become of a serious concern among physicians.
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