超声引导微波消融子宫肌瘤流入血管治疗子宫肌瘤伴月经过多1例

Toshiyuki Kakinuma, Takahumi Ohkusa, Takumi Shinohara, A. Shimizu, Rora Okamoto, M. Kagimoto, Ayaka Kaneko, Kaoru Kakinuma, K. Yanagida, N. Takeshima, M. Ohwada
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摘要

微波子宫内膜消融术(MEA)是一种微创治疗伴有痛经的子宫肌瘤的方法,可以取代传统的子宫切除术。然而,由于术后复发而需要额外治疗的情况经常发生。MEA会烧灼子宫内膜,不建议希望保留生育能力的患者使用。我们报告了一例与子宫肌瘤相关的痛经患者,他们在经阴道超声引导下接受了子宫肌瘤流入血管的微波消融。一名43岁的女性被诊断为慢性粒细胞白血病,两年前接受了达沙替尼治疗。治疗开始后观察到痛经加重。超声和盆腔磁共振成像显示子宫肌瘤。因此,她在经阴道超声引导下接受了MEA。视觉模拟量表评估显示,在痛经和痛经方面有相当大的改善;肌瘤缩小。术后进展顺利,患者于术后第二天出院。未观察到术后并发症。这名患者目前正在接受不孕不育治疗。经阴道超声引导下微波消融肌瘤可以有效、安全地缩小肌瘤大小。这些发现表明,对于那些希望保持生育能力并生育孩子的子宫肌瘤相关痛经患者来说,这种方法是一种新的治疗选择。
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Myoma with Hypermenorrhea Treated with Ultrasound-Guided Microwave Ablation of the Inflowing Blood Vessels to the Uterine Myoma: A Case
Microwave endometrial ablation (MEA) is a minimally invasive treatment for uterine myoma with hypermenorrhea, which can replace conventional hysterectomy. However, cases requiring additional treatment because of postoperative recurrence are often encountered. MEA cauterizes the endometrium and is not recommended for patients who wish to preserve fertility. We present the cases of a patient with myoma-related hypermenorrhea who underwent microwave ablation of the inflowing blood vessels to the uterine myoma under transvaginal ultrasound guidance. A 43-year-old woman was diagnosed with chronic myeloid leukemia and treated with dasatinib 2 years ago. Worsening hypermenorrhea was observed after treatment initiation. Ultrasound and pelvic magnetic resonance imaging revealed a uterine myoma. Therefore, she underwent MEA under transvaginal ultrasound guidance. Visual analog scale evaluation demonstrated considerable improvement in hypermenorrhea and dysmenorrhea; the myoma size showed reduction. The postoperative course was uneventful, and the patient was discharged on the day after surgery. No postoperative complications were observed. This patient is currently undergoing infertility treatment. The microwave ablation of myoma under transvaginal ultrasound guidance can effectively and safely reduce the myoma size. These findings suggest that this method is a novel treatment option for patients with myoma-related hypermenorrhea who wish to preserve their fertility and have children.
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