阻塞性睡眠呼吸暂停治疗概述

Arup Haldar
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引用次数: 0

摘要

一旦被诊断为阻塞性睡眠呼吸暂停(OSA),计划用持续气道正压通气(CPAP)或自动气道正压(APAP)进行滴定,以了解消除睡眠期间气流限制所需的压力。大多数OSA患者都使用这种正压治疗(PAP)设备进行治疗,但这并不是OSA的唯一治疗形式。OSA的静态阻塞可以通过增加内部压力来平衡,而这正是通过PAP治疗来实现的。静态阻塞也可以通过手术来缓解。IOD(口腔内装置)或OPT(口腔压力治疗)是一种在睡眠期间打开上呼吸道或防止塌陷的装置。但睡眠中的动态阻塞,再加上这种静态阻塞,会导致上呼吸道完全或部分关闭。有不同的治疗方法可以解决睡眠中的动态障碍。像肌功能治疗或改善肌肉反应性的设备就是这样的治疗模式。类似地,唤醒阈值或环路增益可以通过不同的药物来解决。有时OSA只发生在特定的褥疮中,可以通过体位治疗来解决。不同形式的治疗可以大致分为三类:初级治疗、替代治疗和辅助治疗。在这篇综述文章中,将简要介绍OSA的不同治疗形式。
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Overview of obstructive sleep apnea treatment
Once diagnosed with obstructive sleep apnea (OSA), a titration with either continuous positive airway pressure (CPAP) or automatic positive airway pressure (APAP) is planned to know the pressure required to abolish the airflow limitation during sleep. Majority of OSA patients are treated with such positive pressure therapy (PAP) devices, but it is not the only form of therapy of OSA. The static obstruction in OSA can be counterbalanced by increasing the pressure from inside and this is being exactly done by PAP therapy. The static obstruction can also be relieved with surgery. IOD (intraoral device) or OPT (oral pressure therapy) is a device which also try to open the upper airway during sleep or prevent collapse. But a dynamic obstruction during sleep, on top of this static obstruction causes complete or partial closure of the upper airway. There are different therapies available to address dynamic obstruction during sleep. Like myofunctional therapy or devices which improve muscle responsiveness are such mode of treatment. Similarly, arousal threshold or loop gain can be addressed with different medications. Sometimes OSA occur only in a particular decubitus and can be addressed with positional therapy. The different form of therapies can be broadly divided into three categories: primary treatment, alternative treatment, and adjunctive treatment. In this review article, a brief description of different forms of therapy in OSA will be presented.
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20 weeks
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