杜阿拉市癌症危险因素的病例对照研究

Engbang Ndamba Jean Paul, E. Henri, M. Valère, Sukam Noutadjeu Diane Sara, Mboudou Emile
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引用次数: 4

摘要

背景:癌症是乳腺细胞的异常增殖。这种疾病和其他癌症在全球范围内都在增加。它是世界上女性最常见的恶性肿瘤,也是一个公共卫生问题。一般来说,在非洲,特别是中非,很少有研究发现癌症的危险因素。正是在这种情况下,我们在杜阿拉市开始了这项研究,以确定这种疾病的风险因素。患者和方法:我们进行了一项病例对照研究,在五年内进行回顾性收集,在七个月内进行前瞻性收集。研究人群均为18岁及以上的女性,根据组织学方案诊断为癌症;以及18岁或18岁以上、体格检查和乳房X光检查正常的女性。我们在杜阿拉市的三家参考医院和两个病理解剖实验室进行了研究。数据是在搜索文件和接受采访的患者处收集的。研究的参数包括:社会人口学特征、临床和准临床参数以及组织学类型。结果:在本研究结束时,癌症主要发生在杜阿拉市的年轻女性身上,她们的中年年龄为44.08±2.6岁。最显著的危险因素是年龄、第一次生育年龄≥30岁、第一次性行为年龄≤18岁、经济水平低、吸烟、激素避孕、生育。结论:最后,乳腺恶性肿瘤在杜阿拉女性人群中占有原始位置,有许多危险因素,如病因。
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Risk Factors for Breast Cancer in the City of Douala: A Case Control Study
Background: The breast cancer is an abnormal proliferation of mammary gland cells. This condition as well as other cancers is globally increasing in the world. It is the most frequent malignancy of women in the world and is a public health problem. Generally in Africa and central Africa in particular, few studies have been realized in search of risk factors of breast cancer. It’s all in this optical we began the study to determine the risk factors of this disease in the city of Douala. Patients and Methods: We conducted a case-control study, gave retrospectives collect on five years and prospectives collect on seven months. The studied population was all women aged 18 years and above with breast cancer diagnostic on histological plan for cases; and women from 18 years or more with normal physical examination and mammography. We have done our research in three reference hospitals of the city of Douala and two laboratories of pathological anatomy. The data were collected at the search files and the patients where interviewed. The parameters studied were: socio-demographic profile, clinic and Para clinic parameters, and the histological type. Results: At the end of this study, breast cancer is predominantly on young women in the city of Douala with a middle age of 44.08 ± 2.6 years. The most significant risk factors were age, age of the first birth ≥ 30 years, age of the first sexual act ≤ 18 years, low economic level, tobacco, hormonal contraceptive, parity. Conclusion: Finally, the malignancy of the breast takes a primordial place within the feminine population of Douala with many risk factors likes causes.
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