菊花对男性生育能力的影响:系统回顾和荟萃分析

IF 0.3 Q4 MULTIDISCIPLINARY SCIENCES Momona Ethiopian Journal of Science Pub Date : 2023-05-21 DOI:10.4314/mejs.v15i1.5
Seid Mohammed, Birhane Alem Berihu, T. Beyene
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引用次数: 0

摘要

文献调查报告称,阿那木提取物不可避免地与生育能力有关。最近的研究表明,沙蚕提取物的水提取物通过影响血清睾酮水平、精子浓度和精子活力,对男性生育能力有不利影响。然而,其证据尚未确定。本文试图确定dill(Anethum graveolens)对男性生育能力影响的证据水平。检索MEDLINE、Cochrane Library、PubMed、Academic Search Complete、SPORT Discus、Science Direct、Scopus、Web of Science和Google Scholar以检索本综述中使用的文献。数据库搜索中使用的关键词是dill、Anethum graveolens、小鼠、雄性生育能力、随机对照试验和实验。搜索仅限于对动物的研究;以英文出版。进行荟萃分析,以检验茴香提取物对男性生育能力的影响。使用Pedro量表评估了证据的总体方法质量。在25项研究中,有4项试验符合本综述的纳入标准。所有研究均纳入荟萃分析。其中,四项研究用于分析精子浓度,三项研究用于精子活力,两项研究用于血清睾酮水平。荟萃分析结果表明,男性生育能力和其他干预措施在诱导男性不孕的效果方面没有显著差异。关于当前主题的研究数量很少。证据的总体质量很低。因此,很难得出dill种子的水提取物是否对雄性生殖能力有不利影响的结论。考虑到我们的荟萃分析,我们建议有必要进行进一步的调查,为dill(Anethum graveolens)对男性生育能力的影响提供充分的证据。
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The Effect of Anethum Graveolens on Male Fertility: Systematic Review and Meta-Analysis
  The literature survey has reported that Anethum graveolens extract is inescapably linked with fertility. Recent studies showed that the aqueous extract of Anethum graveolens extract has an adverse effect on male fertility by affecting serum testosterone level, sperm concentration as well as sperm motility. However, its evidence has not been established. The present paper tries to determine the level of evidence for the effect of dill (Anethum graveolens) on male fertility. MEDLINE, Cochrane Library, PubMed, Academic Search Complete, SPORT Discus, Science Direct, Scopus, Web of Science, and Google Scholar were searched to retrieve the literature used for this review. Keywords utilized across the database search were dill, Anethum graveolens, mice, male fertility, randomized control trial, and experimental. The search was limited to studies in animals; published in the English language. Meta-analysis was conducted to examine the effect of Anethum graveolens (dill) extract administration on male fertility. The overall methodological quality of evidence was assessed using the Pedro scale. Out of 25 studies, four trials met the inclusion criteria for this review. All the studies were included in the meta-analysis. Of these, four studies were included for the analysis of sperm concentration, three studies for sperm motility, and two studies for serum testosterone hormone levels. The meta-analysis results suggested there were no significant differences between male fertility and other interventions in the effects of inducing male infertility. The number of studies regarding the current topic is scarce. The overall quality of evidence was very low. Therefore, it is difficult to conclude whether the aqueous extract of dill seed has or has no adverse effect on male fertility. Considering our meta-analysis, we recommended that there is a need for further investigation to provide adequate evidence for the effect of dill (Anethum graveolens) on male fertility.
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来源期刊
Momona Ethiopian Journal of Science
Momona Ethiopian Journal of Science MULTIDISCIPLINARY SCIENCES-
自引率
0.00%
发文量
13
审稿时长
12 weeks
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