癌症的光动力治疗:基于光敏剂的治疗质量和前景

R. Malviya, Ashutosh Kumar Singh, Ankita Moharana, Vedant Kumar Prajapati, Ashish Kumar Nirmal
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引用次数: 1

摘要

为了杀死癌症细胞,光动力疗法(PDT)利用光敏药物和光。光敏药物被癌细胞吸收。然后由专家用特定的光或激光照射细胞,释放出破坏癌症细胞的氧气。本研究旨在讨论光动力疗法在癌症治疗中的作用、进展和局限性。光敏剂和光敏剂用于光动力学治疗以破坏癌症细胞。激光器或其他光源,例如LED,可以提供照明。有报道称,使用荧光电子显微镜PDT/光热疗法(PTT)双重疗法,一种新型纳米平台用于治疗HER2-过表达的乳腺癌症以及其他原发性和转移性癌症。PDT比传统的癌症疗法有显著的益处,因为它可能导致更少的不良反应。PDT诱导的免疫刺激性细胞死亡和产生强大的局部炎症反应可能导致有效的局部抗癌治疗。PDT的长期发病率和恢复时间低于手术、化疗或放疗。
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Photodynamic Therapy of Cancer: Quality and Prospective of Therapy based on Photosensitizer
To kill cancer cells, photodynamic therapy (PDT) utilizes a light-sensitive medication and light. Light-sensitive drugs are absorbed by cancerous cells. The cells are then illuminated with a specific light or laser by a specialist and oxygen that destroys cancer cells is released. The present study aims to discuss the roles, advancements, and limitations of photodynamic therapy in cancer treatment. Photosensitizers and photosensitizing agents are used in photodynamic treatment to destroy cancer cells. Lasers or other light sources, such as LEDs, may provide illumination. There are reports of a novel nanoplatform for the treatment of HER2-overexpressed breast cancer, as well as other primary and metastatic cancers, using fluorescent electron microscopy PDT/photothermal therapy (PTT) dual-therapy. PDT has a significant benefit over conventional cancer therapies because it may cause fewer adverse effects. PDT-induced immunostimulatory cell death and the production of a robust local inflammatory response might lead to effective local anticancer therapy. PDT has a lower long-term morbidity and recovery time than surgery, chemotherapy, or radiation.
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来源期刊
CiteScore
1.00
自引率
0.00%
发文量
50
期刊介绍: Current Cancer Therapy Reviews publishes frontier reviews on all the latest advances in clinical oncology, cancer therapy and pharmacology. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in cancer therapy.
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