突尼斯中部地区淡纹库蚊对双硫磷的抗药性水平及相关机制研究

J. Daaboub, A. Tabbabi, Ali Lamari, M. Feriani, C. Boubaker, H. B. Cheikh
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引用次数: 5

摘要

对在突尼斯中部采集的五个库蚊种群对特马福思的易感性进行了评估。样品#5的抗性水平较高(>50倍),而其他抗性样品的抗性水平较低,不超过4倍。LC50显示了样品#2的易感性。在三个样本中发现CYP450酶与特马福思耐药性有关。事实上,在灭磷生物测定中添加Pb完全抑制了样品#1(RR50=0.84,p>0.05,RSR=3.0)和样品5(RR50=1.5,p>0.05,RSR=37.1)的耐药性。在最易感的样品中,样品#3的灭磷耐药性水平略有下降(RR=1.9,p75%)。突尼斯迫切需要取代杀虫剂特马福思,继续控制库蚊。
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Levels of Insecticide Resistance to Temephos, and Associated Mechanisms in Culex pipiens Mosquitoes from Central Tunisia
Five populations of Culex pipiens collected in central Tunisia were evaluated for their susceptibility to temephos. The resistance level was high for samples # 5 (>50-fold), and low, not exceeding 4-fold in the other resistant samples. LC 50 showed the susceptibility of sample # 2. The CYP450 enzyme was found related to temephos resistance in three samples. In fact, the addition of Pb to temephos bioassays completely suppressed the resistance in samples # 1 (RR 50 =0.84, p>0.05, RSR=3.0) and 5 (RR 50 =1.5, p>0.05, RSR=37.1). The temephos resistance level of sample # 3 decreased slightly (RR=1.9, p 75%) were recorded in the most susceptible samples. There is an urgent need to replace the insecticide temephos for continued control of Culex pipiens in Tunisia.
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