Sirenomelia with major cardiac anomalies

Sirenomelia is a rare and serious congenital anomaly characterised by fusion of the lower limbs, usually a single umbilical artery and malformations of the genitourinary and gastrointestinal tracts. In this report, we present clinical and radiological features, as well as autopsy findings, in a patient with sirenomelia diagnosed at the time of delivery. Major cardiac defects were observed, namely transposition of the great vessels and a hypoplastic left ventricle.