标准中药PM014方通过抑制TGF-β1信号通路改善新冠肺炎患者肺纤维化

Maryam Allahverdi-Khani, L. Ulloa, M. Motaghinejad, Mahsa Salehirad
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引用次数: 0

摘要

许多研究先前已经提供了关于植物衍生化合物抗炎特性的证据,这些化合物可以预防肺损伤。在这项研究中,我们试图分析PM 014对新冠肺炎炎症和肺纤维化的治疗效果,并描述与冠状病毒肺炎(新冠肺炎)相关的最具挑战性问题之一的治疗方法。我们认为,从各个角度仔细研究所提出的机制,超出了设计新策略以提供适当治疗的生理后果。
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Standardized Herbal PM014 Formula Ameliorates Pulmonary Fibrosis in COVID-19 Patients by Inhibiting the TGF-β1 Signaling Pathway
A number of studies have previously provided evidence on the Anti-inflammatory properties of plant-derived compounds that can prevent lung injury. In this study, we attempted to analyze the therapeutic effects of PM 014 on inflammation and pulmonary fibrosis in COVID-19 as well as describing the treatment of one of the most challenging problems related to the coronavirus-19 (COVID-19). We believe that having a close look at all angles of the proposed mechanism goes beyond the physiological consequences of a way to design new strategies for providing an appropriate treatment.
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CiteScore
0.90
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