碳氢化合物相关毒性:一系列案例及文献综述

Ishan Lamba, D. Jadhav
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引用次数: 0

摘要

背景:碳氢化合物相关毒性(HAT)是一种新出现的威胁,与大规模工业化和容易获得含碳氢化合物有关。碳氢化合物具有独特的毒理学特征,管理相关中毒症状的原则与其他毒素有很大不同。病例报告:在这里,我们介绍了一系列病例,并对现有文献进行了深入审查,以显示与这些看似无害的化学品相关的风险,以及已批准的治疗暴露患者的指南。在这三种情况下,碳氢化合物都是杀虫剂的稀释剂。摄入的农药量是无毒的,而碳氢化合物对肺部造成了与剂量无关的物理毒性。讨论:碳氢化合物相关的毒性经常被忽视,因为它们被用作各种其他有毒化学品的稀释剂。它们的治疗方法通常不同于可能与它们一起食用的其他毒素,尽管数量不多。结论:在消耗的毒素中识别碳氢化合物稀释剂标志着正确治疗的第一步。正确标记含有碳氢化合物的化学溶液将大大有助于识别这些毒素。
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Hydrocarbon Associated Toxicities: a Case Series and Review of Literature
Background: Hydrocarbon associated toxicity (HAT) is an emerging threat related to wide scale industrialization and easy access to hydrocarbon-containing chemical compounds. Hydrocarbons have a unique toxicological profile and the principles of managing related toxidromes are considerably different from other toxins. Case reports: Here, we present a case series and in-depth review of the existing literature to show the risks associated with these seemingly harmless chemicals, and the approved guidelines for treating exposed patients. In all three cases, the hydrocarbon was a diluent for a pesticide. The amount of pesticide ingested was nontoxic, while the hydrocarbons caused a dose-independent physical toxicity to the lungs. Discussion: Hydrocarbon associated toxicities often go unnoticed because of their usage as diluents for various other toxic chemicals. Their treatment usually differs from other toxins that may have been consumed with them, albeit in insignificant quantities. Conclusion: Recognition of a hydrocarbon diluent in a consumed toxin marks the first step in the correct treatment. Correct labeling of chemical solutions containing hydrocarbons would go a long way in identifying these toxins.
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来源期刊
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审稿时长
12 weeks
期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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