{"title":"先天性B细胞免疫在癌症预防中的核心作用","authors":"N. Tupitsyn","doi":"10.4236/ABC.2021.111002","DOIUrl":null,"url":null,"abstract":"There are some forgotten items. There is a specific way to eradicate cancer cells at the very early stage of their appearance. Natural humoral \nimmunity with CD5+ B-cell produced pentameric IgM to cancer associated glycans \nnormally to eliminate arising cancer cells. This branch of innate immunity is \ndecreasing with age and that is a basis for selective immunodeficieny which may \nbe corrected. This area of research was well studied and proved by the team of \nProf. Vollmers (Germany), but then forgotten for about 15 years.","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Central Role of Innate B-Cell Immunity in Cancer Prevention\",\"authors\":\"N. Tupitsyn\",\"doi\":\"10.4236/ABC.2021.111002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"There are some forgotten items. There is a specific way to eradicate cancer cells at the very early stage of their appearance. Natural humoral \\nimmunity with CD5+ B-cell produced pentameric IgM to cancer associated glycans \\nnormally to eliminate arising cancer cells. This branch of innate immunity is \\ndecreasing with age and that is a basis for selective immunodeficieny which may \\nbe corrected. This area of research was well studied and proved by the team of \\nProf. Vollmers (Germany), but then forgotten for about 15 years.\",\"PeriodicalId\":59114,\"journal\":{\"name\":\"生物化学进展(英文)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"生物化学进展(英文)\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.4236/ABC.2021.111002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"生物化学进展(英文)","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.4236/ABC.2021.111002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Central Role of Innate B-Cell Immunity in Cancer Prevention
There are some forgotten items. There is a specific way to eradicate cancer cells at the very early stage of their appearance. Natural humoral
immunity with CD5+ B-cell produced pentameric IgM to cancer associated glycans
normally to eliminate arising cancer cells. This branch of innate immunity is
decreasing with age and that is a basis for selective immunodeficieny which may
be corrected. This area of research was well studied and proved by the team of
Prof. Vollmers (Germany), but then forgotten for about 15 years.