关节中四氢大麻素的浓度

IF 0.9 Q3 Psychology Drugs and Alcohol Today Pub Date : 2021-02-11 DOI:10.1108/DAT-07-2020-0050
Eduardo Tejedor Tejada, Domiciana De la Fuente Marcos, Maria Jesus Cuesta Lozano, J. González, Jesús Moro Aguado, Jesús Tejedor Muñoz
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引用次数: 0

摘要

目的本研究旨在评估Δ-9-四氢大麻酚(THC)和大麻二酚(CBD)在大麻关节中的效力和剂量。这将能够更好地估计用户的暴露程度,并有助于更好地了解潜在的有害影响。设计/方法/方法2017年至2019年卡斯蒂利亚-莱昂自治区(西班牙)执法部门在街上没收的完整大麻关节的分析 = 744)。关节含有大麻和烟草(N = 729),平均净重0.69 g(IQR = 0.28);THC浓度中位数为6.30%(IQR = 4.51)和四氢大麻酚中位剂量42 mg(IQR = 32.75)。共有35.5%的混合节理含有CBN——中值百分比0.61%(IQR = 0.51)。CBD在混合关节中的检出率为10.3%,中位数为0.13%(IQR = 0.12)和中位剂量1 mg(IQR = 0.92)。CBD/THC比率的中值为0.02(IQR = 0.02)。分析的样本包括纯大麻关节(N = 15) ,THC中位数为11.86%(IWR = 6.30)或中位剂量118 mg.原始性/value研究发现,大麻关节中四氢大麻酚和CBD的浓度和剂量都很高,这对使用者的高暴露量和相关的潜在后果发出了警告。所获得的结果为标准大麻单位的定义提供了新的视角。
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Concentration of tetrahidrocannabinol in joints
Purpose This study aims to assess the potency and dose of Δ-9-Tetrahidrocannabinol (THC) and Cannabidiol (CBD) in cannabis joints. This will enable better estimates of the degree of exposure in a user and contribute towards a better understanding of potential harmful effects. Design/methodology/approach Analysis of intact joints confiscated by law enforcement on the street in the autonomous region of Castilla y León (Spain) during the years 2017–2019. Findings This study analysed THC, CBN and CBD in marijuana joints (N = 744). Joints contain cannabis and tobacco (N = 729), had a median net weight 0.69 g (IQR = 0.28); concentration THC median was 6.30%(IQR = 4.51) and THC median dose 42 mg (IQR = 32.75). A total of 35.5% mixed joints contained CBN – median percentage 0.61% (IQR = 0.51). CBD was detected 10.3% of mixed joints – median percentage 0.13% (IQR = 0.12) and median dose 1 mg (IQR = 0.92). CBD/THC ratio presented median value of 0.02 (IQR = 0.02). The samples analysed comprised pure cannabis joints (N = 15), with THC median 11.86% (IWR = 6.30) or median dose of 118 mg. Originality/value The study found high values for concentration and dose of THC and CBD in cannabis joints, warning of high exposures for the user and associated potential consequences. The results obtained contribute new perspectives on the definition of a standard cannabis unit.
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Drugs and Alcohol Today
Drugs and Alcohol Today SUBSTANCE ABUSE-
CiteScore
1.60
自引率
0.00%
发文量
1
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