Artificial Intelligence via Competitive Learning and Image Analysis for Endometrial Malignancies

Objective of this study is to investigate the potential of an artificial intelligence (AI) technique, based on competitive learning, for the discrimination of benign from malignant endometrial nuclei and lesions. For this purpose, 416 liquid-based cytological smears with histological confirmation were collected, each smear corresponded to one patient. From each smear was extracted nuclear morphometric features by the application of an image analysis system. Subsequently nuclei measurement from 50% of the cases were used to train the AI system to classify each individual nucleus as benign or malignant. The remaining measurement, from the unused 50% of the cases, were used for AI system performance evaluation. Based on the results of nucleus classification the patients were discriminated as having benign or malignant disease by a secondary subsystem specifically trained for this purpose. Based on the results it was conclude that AI based computerized systems have the potential for the classification of both endometrial nuclei and lesions.