寨卡病毒感染相关脊髓炎研究进展

Q4 Immunology and Microbiology 中华微生物学和免疫学杂志 Pub Date : 2019-10-31 DOI:10.3760/CMA.J.ISSN.0254-5101.2019.10.013

Geng Miao, Cuiling Ding, Yangang Liu, Z. Qi

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引用次数: 0

摘要

寨卡病毒属于黄病毒科黄病毒属，主要通过伊蚊传播给人类。2015年在南美洲爆发的寨卡病毒感染引起了全世界的健康担忧，因为小头症、格林-巴利综合征和脊髓炎的发病率不断增加，尽管大多数患者没有症状。为了进一步了解和阐明寨卡病毒感染相关脊髓炎的致病机制，本文综述了寨卡病毒的生物学特性、传播和治疗的最新进展，以及相关病例报告和可能的机制。关键词：寨卡病毒；脊髓炎；致病机制

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Advance in Zika virus infection-related myelitis

Zika virus belongs to the family Flaviviridae, genus Flavivirus and is mainly transmitted to humans by Aedes. The outbreak of Zika virus infection in South America in 2015 raised worldwide health concern due to the increasing incidence of microcephaly, Guillain-Barre syndrome and myelitis, although most of the patients were asymptomatic. Here, to further understand and elucidate the pathogenic mechanism of Zika virus infection-associated myelitis, this review summarized the latest advance in biological characteristics, transmission and treatment of Zika virus infection as well as the related case reports and possible mechanisms. Key words: Zika virus; Myelitis; Pathogenic mechanism

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来源期刊

中华微生物学和免疫学杂志 Immunology and Microbiology-Virology

CiteScore

0.50

自引率

0.00%

发文量

6906

期刊介绍： Chinese Journal of Microbiology and Immunology established in 1981. It is one of the series of journal sponsored by Chinese Medical Association. The aim of this journal is to spread and exchange the scientific achievements and practical experience in order to promote the development of medical microbiology and immunology. Its main contents comprise academic thesis, brief reports, reviews, summaries, news of meetings, book reviews and trends of home and abroad in this field. The distinguishing feature of the journal is to give the priority to the reports on the research of basic theory, and take account of the reports on clinical and practical skills.