{"title":"妊娠期埃文斯综合征——一名妇女两次成功妊娠的病例报告;文献综述。","authors":"N. Navakumar","doi":"10.31579/2690-4861/229","DOIUrl":null,"url":null,"abstract":"Evans syndrome is a rare autoimmune disease in which an individual's antibodies attacks the body's own red Autoimmune blood cells and platelets. There is a coexistence of Immune thrombocytopenia (ITP) with haemolytic anaemia (AIHA) with immune neutropenia sometimes in the absence of known underlying etiology.1Association of Evans syndrome with pregnancy is very rare, and only a few cases have been published in medical literature. No definite treatment protocols are defined. Treatment options during pregnancy are further limited due to concerns of teratogenic effect of pharmacological agents. Evans syndrome can be diagnosed with a full blood count film and a direct Coombs test. We describe here a rare case that was diagnosed as secondary Evans syndrome with SLE complicating pregnancy that resulted in two live births in a woman. We have also briefly discussed the pathophysiology, clinical features, diagnosis and the possible treatment options and outcome of Evans syndrome in pregnancy","PeriodicalId":93010,"journal":{"name":"International journal of clinical case reports and reviews : open access","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evans Syndrome in pregnancy – Case report of two successful pregnancies in a woman ; Review of Literature.\",\"authors\":\"N. Navakumar\",\"doi\":\"10.31579/2690-4861/229\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Evans syndrome is a rare autoimmune disease in which an individual's antibodies attacks the body's own red Autoimmune blood cells and platelets. There is a coexistence of Immune thrombocytopenia (ITP) with haemolytic anaemia (AIHA) with immune neutropenia sometimes in the absence of known underlying etiology.1Association of Evans syndrome with pregnancy is very rare, and only a few cases have been published in medical literature. No definite treatment protocols are defined. Treatment options during pregnancy are further limited due to concerns of teratogenic effect of pharmacological agents. Evans syndrome can be diagnosed with a full blood count film and a direct Coombs test. We describe here a rare case that was diagnosed as secondary Evans syndrome with SLE complicating pregnancy that resulted in two live births in a woman. We have also briefly discussed the pathophysiology, clinical features, diagnosis and the possible treatment options and outcome of Evans syndrome in pregnancy\",\"PeriodicalId\":93010,\"journal\":{\"name\":\"International journal of clinical case reports and reviews : open access\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of clinical case reports and reviews : open access\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31579/2690-4861/229\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of clinical case reports and reviews : open access","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31579/2690-4861/229","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evans Syndrome in pregnancy – Case report of two successful pregnancies in a woman ; Review of Literature.
Evans syndrome is a rare autoimmune disease in which an individual's antibodies attacks the body's own red Autoimmune blood cells and platelets. There is a coexistence of Immune thrombocytopenia (ITP) with haemolytic anaemia (AIHA) with immune neutropenia sometimes in the absence of known underlying etiology.1Association of Evans syndrome with pregnancy is very rare, and only a few cases have been published in medical literature. No definite treatment protocols are defined. Treatment options during pregnancy are further limited due to concerns of teratogenic effect of pharmacological agents. Evans syndrome can be diagnosed with a full blood count film and a direct Coombs test. We describe here a rare case that was diagnosed as secondary Evans syndrome with SLE complicating pregnancy that resulted in two live births in a woman. We have also briefly discussed the pathophysiology, clinical features, diagnosis and the possible treatment options and outcome of Evans syndrome in pregnancy