在C(7)-C(8)键上有两个杂原子的含氧杂环环化色酮的合成

IF 0.4 Q4 CHEMISTRY, ANALYTICAL French-Ukrainian Journal of Chemistry Pub Date : 2019-07-30 DOI:10.17721/FUJCV7I1P121-139
T. V. Shokol, N. Gorbulenko, V. Khilya
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引用次数: 0

摘要

本综述介绍了在C(7)-C(8)键上与具有两个杂原子的五元、六元和七元含氧杂环环化的色酮的先进合成策略,如6H-[1,3]二氧杂环[4,5-h]色烯-6-酮、2,3-二氢-7H-[1,4]二氧杂并[2,3-h]色酮-7-酮、3,4-二氢-2H、8H-[1.4]二氧环并[2,3-h]色烯-8-酮、2,3-二氢-1H,7H-铬并[7,8-b][1,4]恶嗪-7-酮、4H,12H-吡喃并[2,3-a]吩恶嗪-4-酮和9,10-二氢-4H,8H-铬并[8,7-e][1,3]恶嗪-4-酮类。天然存在和修饰的合成稠合杂芳烃的生物活性也得到了强调。
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Synthesis of chromones, annulated with oxygen-containing heterocycles with two hetero atoms at C(7)-C(8) bond
The present review represented the advanced synthetic strategies for chromones annulated at the C(7)-C(8) bond with five-membered, six-membered, and seven-membered oxygen-containing heterocycles with two heteroatoms, such as 6H-[1,3]dioxolo[4,5-h]chromen-6-one, 2,3-dihydro-7H-[1,4]dioxino[2,3-h]chromen-7-one, 3,4-dihydro-2H,8H-[1,4]dioxepino[2,3-h]chromen-8-one, 2,3-dihydro-1H,7H-chromeno[7,8-b][1,4]oxazin-7-one, 4H,12H-pyrano[2,3-a]phenoxazine-4-one and 9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]oxazin-4-one. The biological activity of naturally occurring and modified synthetic fused hetarenochromones has been also highlighted.
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来源期刊
French-Ukrainian Journal of Chemistry
French-Ukrainian Journal of Chemistry CHEMISTRY, ANALYTICAL-
自引率
0.00%
发文量
13
审稿时长
4 weeks
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