班墩干区金屯干村农民尿镉水平致肾功能损害

Poppi Nastasia Yunita Dewi, N. Nurjazuli, B. Budiyono
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引用次数: 0

摘要

简介:三宝垄县农民在蔬菜种植中施用杀虫剂以控制害虫。杀虫剂的活性成分之一是镉,人体接触镉会干扰肾功能。大量接触镉可能导致慢性肾功能衰竭。如果体内有大量的游离镉离子,肾脏产生金属硫蛋白的能力就会降低。因此,它可能会损害肾小管,因为它会导致高水平的尿镉,这可能是有毒的。本研究旨在分析农民尿镉水平与肾功能受损之间的关系。方法:本研究采用分析观察法,采用横断面研究设计。本研究中的人口都是三宝垄县班顿甘区金通甘村的农民,多达406人。通过有针对性的抽样,选择了60人作为样本。结果与讨论:农民尿Cd水平平均为0.958µg/L,标准偏差为0.570µg/L。Cd含量最高为5.390µg/L,最低为<0.100µg/L。统计卡方检验结果表明,尿Cd水平与肾功能损害之间存在相关性(p=0.041)。
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Urinary Cadmium Level Causing Impaired Kidney Function in Farmers in Gintungan Village, Bandungan District
Introduction: Farmers apply pesticides to control pests on vegetable farming in Semarang regency. One of the active ingredients of pesticides is cadmium (Cd), and exposure to cadmium in humans can interfere with kidney function. High exposure to Cd may cause the effects of chronic kidney failure. If there are a lot of free Cd ions in the body, the ability of the kidneys to produce metallothionein will be reduced. Thus, it may damage the kidney tubules as it results in high levels of urinary Cd which can be toxic. This study aimed to analyze an association between the levels of urinary Cd and impaired kidney function in farmers. Methods: This study was analytic observational and used design a cross-sectional study design. The population in this study was all farmers as many as 406 people in Gintungan village, Bandungan district, Semarang regency. There were 60 people selected as samples through purposive sampling. Results and Discussion: The level of urinary Cd in farmers on average was 0.958 µg/L with a standard deviation of 0.570 µg/L. The highest level of Cd was 5.390 µg/L and the lowest was < 0.100 µg/L. The results of the statistical chi-square test showed there was an association between levels of urinary Cd and impaired kidney function (p = 0.041). Conclusion: Impaired kidney function in farmers in Gintungan might be caused by the level of urinary Cd. Further research should measure creatinine in the blood to ensure a decrease in the glomerular filtration rate in the kidneys of the farmers.
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1.00
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0.00%
发文量
32
审稿时长
16 weeks
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