{"title":"常规跑步机运动改善月经期造血干细胞和姜黄素负载纳米复合水凝胶治疗的大鼠脊髓损伤修复：一项体内外研究","authors":"Rui Cong, Fenglei Li","doi":"10.1166/sam.2023.4449","DOIUrl":null,"url":null,"abstract":"In the current study, the synergistic healing efficacy of regular treadmill exercise and administration of menstrual blood stem cells and curcumin-loaded calcium alginate hydrogel was investigated. In Vitro studies were used to characterize the hydrogel system In Vitro.\n Various validation methods including BBB assay, histopathological examinations, and gene expression studies were used to assess the healing efficacy of different groups. Study showed that treadmill exercise and the hydrogels loaded with both menstrual blood stem cells and curcumin significantly\n improved the spinal cord injury repair through upregulation of pro-healing genes.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Regular Treadmill Exercise Improves the Spinal Cord Injury Repair in a Rat Model Treated with Menstrual Blood Stem Cells and Curcumin-Loaded Nanocomposite Hydrogel: An In Vitro and In Vivo Study\",\"authors\":\"Rui Cong, Fenglei Li\",\"doi\":\"10.1166/sam.2023.4449\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the current study, the synergistic healing efficacy of regular treadmill exercise and administration of menstrual blood stem cells and curcumin-loaded calcium alginate hydrogel was investigated. In Vitro studies were used to characterize the hydrogel system In Vitro.\\n Various validation methods including BBB assay, histopathological examinations, and gene expression studies were used to assess the healing efficacy of different groups. Study showed that treadmill exercise and the hydrogels loaded with both menstrual blood stem cells and curcumin significantly\\n improved the spinal cord injury repair through upregulation of pro-healing genes.\",\"PeriodicalId\":21671,\"journal\":{\"name\":\"Science of Advanced Materials\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Science of Advanced Materials\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1166/sam.2023.4449\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science of Advanced Materials","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1166/sam.2023.4449","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Regular Treadmill Exercise Improves the Spinal Cord Injury Repair in a Rat Model Treated with Menstrual Blood Stem Cells and Curcumin-Loaded Nanocomposite Hydrogel: An In Vitro and In Vivo Study
In the current study, the synergistic healing efficacy of regular treadmill exercise and administration of menstrual blood stem cells and curcumin-loaded calcium alginate hydrogel was investigated. In Vitro studies were used to characterize the hydrogel system In Vitro.
Various validation methods including BBB assay, histopathological examinations, and gene expression studies were used to assess the healing efficacy of different groups. Study showed that treadmill exercise and the hydrogels loaded with both menstrual blood stem cells and curcumin significantly
improved the spinal cord injury repair through upregulation of pro-healing genes.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
