{"title":"腹膜透析引起的腹膜间隔性腹膜炎：危及生命但可治愈","authors":"Theerachai Thammathiwat , Sajja Tatiyanupanwong , Uraiwan Parinyasiri , Dhammika Leshan Wannigama , Tanittha Chatsuwan , Talerngsak Kanjanabuch","doi":"10.1016/j.mmcr.2023.100612","DOIUrl":null,"url":null,"abstract":"<div><p>Two cases of PD-associated peritonitis due to <em>Cunninghamella</em> (<em>C. bertholletiae</em> and <em>C. guizhouensis</em>) were reported here with favorable outcomes, albeit presenting with septicemia. Both patients presented with classic features of bacterial peritonitis, cloudy effluent with a neutrophil predominance, followed by fever and septicemia/septic shock. The pathogen species were confirmed and verified by molecular phylogeny using universal and specific fungal primers. All isolations were susceptible/intermediately susceptible to amphotericin B but resistant to other antifungal agents, including triazoles, caspofungin, and terbinafine. Both cases were successfully treated with timely PD catheter removal and antifungal medications for 2–4 weeks.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"42 ","pages":"Article 100612"},"PeriodicalIF":1.6000,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/fb/main.PMC10579521.pdf","citationCount":"0","resultStr":"{\"title\":\"Peritoneal dialysis-associated peritonitis from pauci-septated mold: Life-threatening but curable\",\"authors\":\"Theerachai Thammathiwat , Sajja Tatiyanupanwong , Uraiwan Parinyasiri , Dhammika Leshan Wannigama , Tanittha Chatsuwan , Talerngsak Kanjanabuch\",\"doi\":\"10.1016/j.mmcr.2023.100612\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Two cases of PD-associated peritonitis due to <em>Cunninghamella</em> (<em>C. bertholletiae</em> and <em>C. guizhouensis</em>) were reported here with favorable outcomes, albeit presenting with septicemia. Both patients presented with classic features of bacterial peritonitis, cloudy effluent with a neutrophil predominance, followed by fever and septicemia/septic shock. The pathogen species were confirmed and verified by molecular phylogeny using universal and specific fungal primers. All isolations were susceptible/intermediately susceptible to amphotericin B but resistant to other antifungal agents, including triazoles, caspofungin, and terbinafine. Both cases were successfully treated with timely PD catheter removal and antifungal medications for 2–4 weeks.</p></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"42 \",\"pages\":\"Article 100612\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/fb/main.PMC10579521.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211753923000441\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753923000441","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Peritoneal dialysis-associated peritonitis from pauci-septated mold: Life-threatening but curable
Two cases of PD-associated peritonitis due to Cunninghamella (C. bertholletiae and C. guizhouensis) were reported here with favorable outcomes, albeit presenting with septicemia. Both patients presented with classic features of bacterial peritonitis, cloudy effluent with a neutrophil predominance, followed by fever and septicemia/septic shock. The pathogen species were confirmed and verified by molecular phylogeny using universal and specific fungal primers. All isolations were susceptible/intermediately susceptible to amphotericin B but resistant to other antifungal agents, including triazoles, caspofungin, and terbinafine. Both cases were successfully treated with timely PD catheter removal and antifungal medications for 2–4 weeks.
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